… activity was initially described in the 1990s, including transgenic studies that established
each enzyme’s essential role in animal development 4 . Discoveries of new enzymes and …

… DNA methylation (cytosine/adenine) in plants, its functions in regulating gene expression
under abiotic/biotic stresses, developmental … (de)methylation in animals have been understood. …

… mechanisms in DNA methylation establishment during gametogenesis. Why oocyte and
sperm employ different H3K36 methylation to guide de novo DNA methylation awaits further …

… To explore the functional importance of genome-scale DNA methylation during sheep … the
genome-wide DNA methylation profiles at key stages of Hu sheep developmental (fetus and …

… and can be used as a reference for studies on animal breeding, muscle biology and related
diseases. Going forward, it would be informative to integrate these data with epigenetic …

… A quarter century ago, one of the pioneers in the field of DNA methylation, Rudolf Jaenisch,
… about DNA methylation and speculated in which developmental contexts it might function [ …

… in gDMR methylation at the 8… methylation maintenance, but presence of the alternative
imprint regulator ZNF445. In conclusion, our study reveals species differences in DNA methylation …

… development. In this study, we sought to investigate the effects of genome-wide DNA methylation
… component of meat, is one of the most important agricultural animal economic traits. It is …

… HD transgenic sheep generated from a new large-animal HD transgenic ovine model 24
. Sheep (Ovis aries L.) were selected because the developmental pattern of the ovine basal …

… sequence encodes a default epigenetic “ground state” for each genomic region, to which
its DNA methylation is reset in early embryonic development 80 . Nevertheless, here we use …