DNA methylation: a historical perspective

AL Mattei, N Bailly, A Meissner - Trends in Genetics, 2022 - cell.com
… rapidly growing number of base-resolution methylation maps. Despite this, several … of DNA
methylation patterns remain under investigation. Here, we review the field of DNA methylation

Maternal smoking during pregnancy is associated with DNA methylation in early adolescence: A sibling comparison design.

N Nonkovic, K Marceau, JE McGeary… - Developmental …, 2024 - psycnet.apa.org
… impact offspring biological (eg, deoxyribonucleic acid methylation [DNAm]) and behavioral
(… ) development. There has been consistency in findings of differential methylation in global …

Neuroimaging and DNA methylation: an innovative approach to study the effects of early life stress on developmental plasticity

ILC Mariani Wigley, E Mascheroni, D Peruzzo… - Frontiers in …, 2021 - frontiersin.org
… All the studies included in this review highlighted the role of early life stress on DNA
methylation of different genes and the variability in brain function (Harms et al., 2017; Swartz et al., …

Aneuploidy and DNA methylation as mirrored features of early human embryo development

EN Tolmacheva, SA Vasilyev, IN Lebedev - Genes, 2020 - mdpi.com
… The associations of these two phenomena are well studied in the context of carcinogenesis,
but here, we consider the relationship of DNA methylation and aneuploidy in early human …

Differential DNA methylation by early versus late parenteral nutrition in the PICU: a biological basis for its impact on emotional and behavioral problems documented 4 …

A Jacobs, F Güiza, I Verlinden, K Dulfer… - Clinical …, 2021 - Springer
… long-term health and development through induction of DNA methylation changes [15,16,17].
The early-PN-induced aberrant alterations in DNA methylation that we have identified in …

[HTML][HTML] Repression of FGF signaling is responsible for Dnmt3b inhibition and impaired de novo DNA methylation during early development of in vitro fertilized …

W Fu, Y Yue, K Miao, G Xi, C Zhang… - … Journal of Biological …, 2020 - ncbi.nlm.nih.gov
DNA methylation during early development 26 , 28 , we next attempted to test if Dnmt3b was
inhibited in IVF embryos during early development. … /DNMT3B in early embryos, which may …

Genome-Wide DNA Methylation in Early-Onset-Dementia Patients Brain Tissue and Lymphoblastoid Cell Lines

O Ramos-Campoy, A Comas-Albertí, D Hervás… - International Journal of …, 2024 - mdpi.com
DNA methylation study conducted on groups of patients with familial and sporadic forms
of early-… Previous evidence regarding methylation alterations in brain samples from AD patients …

Early developmental carry‐over effects on exploratory behaviour and DNA methylation in wild great tits (Parus major)

B Sepers, KJF Verhoeven… - Evolutionary …, 2024 - Wiley Online Library
methylation later in life. We propose that treatment-associated DNA methylation differences
may … , rather than that they are directly induced by the environment during early development. …

DNA methylation profiles suggest intergenerational transfer of maternal effects

CJ Venney, OP Love, EJ Drown… - Molecular Biology and …, 2020 - academic.oup.com
… Our results indicate maternal effects on offspring DNA methylation in early development
are gene-specific. We found transient gene-specific dam effects at the eyed egg and alevin …

Diagnostic power of DNA methylation classifiers for early detection of cancer

D Roy, M Tiirikainen - Trends in cancer, 2020 - cell.com
DNA methylation-based epigenetic signatures … DNA-methylation profiling for noninvasive
diagnosis of early stage cancers and discuss the advanced analytical approaches developed