… stretches of hypermethylated DNA in CpG-dense promoter regions of the genes. We, … -based
DNA methylation analyses. We found specific DNA methylation profiles in pediatric MB …

… tumor in children, exhibits highly dysregulated DNA methylation. … Here, we detected global
5hmC levels in two independent … DNA for each sample (1 μg) was denatured by heating at 100…

… Medulloblastoma is a malignant childhood brain tumor and … Epigenetics is widely defined
as heritable alterations in gene … Our research on DNA methylation levels of MB showed that …

… Survival rates in children vary depending on the patient’s … have been identified in children
with medulloblastoma, WNT-… the standard conditions: initial denaturation at 95C for thirty …

… DNA methylation has been explored as a potential driver, … Additionally, our study consists
primarily of medulloblastomas, … Cycle parameters were as follows: denaturation at 94 C 30 s, …

… , and it is uncertain its role in the disease development and … the basis for the identification of
target genes involved in the initiation … patterns of DNA methylation, gene expression profiles, …

… alterations in group 1 and 2 medulloblastomas with … DNA methylation has been explored
as a potential driver, … PCR cycle parameters were as follows: denaturation at 95 C for 30 …

… (SHH-MB) is one of the most common malignant pediatric … participates in regulation of
cerebellar development. Here … studies have identified gene mutations, aberrant DNA methylation, …

… genetic aberrations present in the tumor cells and are found … on WGS data enables the
development of highly sensitive … at 94 C for 30 s (denaturation) and individualized annealing …

… -sequencing, and DNA methylation arrays, we demonstrate … rare childhood brain tumor
entities, including medulloblastoma, … Briefly, probes were co-denatured with the target cells on a …