… are alternatively polyadenylated depending on the parental origin of DNA methylation at the
iCGI … Blocking spurious intragenic transcriptional activity is a method to ensure productive …

… DNA methylation status of these iCGIs is dependent upon their host gene transcriptional activity
… determine the influence of intragenic transcription and DNA methylation on host gene pre…

… start sites), intragenic (within gene bodies) and intergenic (in … effects of DNA methylation on
transcriptional activity between … intragenic CGIs (iCGIs) – while there is consensus over the …

… silenced through DNA methylation (5mC) and methyl-CpG … of CGIs prime them for
transcriptional activity. The discovery … dependent on CpG density alone [41]. In mESCs, some CGIs …

… (CGIs) that are refractory to DNA methylation. CGIs integrate … gene promoters and correlates
with transcriptional activity. … primarily relies on site-specific DNA-binding transcription factors …

… and intergenic CpG dinucleotides. Seventy percent of all promoters contain … DNA
hypermethylation propose an “instructive mechanism” of aberrant DNA methylation in tumors that …

… be inhibited by DNA methylation, as the motif contains two CpG dinucleotides and … for
transcription 2 . Our findings instead argue that activation of at least a subset of CGIs critically relies …

… Species with larger genomes have higher levels of intergenic DNA methylation, which is
mostly … The presence of TEs at these locations was dependent on their evolutionary age, as …

… TET-dependent, “active” demethylation at these CpGs. More … residing in regions of different
transcriptional activity (Fig. 4b). … that CpGs residing in the proximity of CpG island shores can …

… DNA methylation is considered to be the predominant … The occurrence of non-CpG methylation
at known CpG islands … Methylation at non-CpG sites is thus dependent on both internal …