Co-methylation analyses identify CpGs associated with lipid traits in Chinese discordant monozygotic twins

Z Li, W Wang, W Li, H Duan, C Xu, X Tian… - Human Molecular …, 2024 - academic.oup.com
… ICE FALCON indicated abnormal TC was regarded as the consequence of DNA methylation
in … Our results indicated that DNA methylation levels of 12 CpGs in GATA4, ITFG2-AS1, and …

[HTML][HTML] Differentially methylated and expressed genes in familial type 1 diabetes

M Dashti, R Nizam, P Hebbar, S Jacob, SE John… - Scientific Reports, 2022 - nature.com
DNA methylation studies in the larger populations 8,10 . Secondly, gene expression profiles
… three families in our study to integrate with DNA methylation events is probably not the best …

[HTML][HTML] Epigenetic differences in inflammation genes of monozygotic twins are related to parent-child emotional availability and health

CR Lewis, HA Sowards, MJ Huentelman… - Brain, Behavior, & …, 2020 - Elsevier
… For this reason, we used a monozygotic (MZ) twin difference design to control for genetic …
on DNA methylation. Because MZ twins largely share the same DNA, any differences in DNA

[HTML][HTML] Genetic impacts on DNA methylation: research findings and future perspectives

S Villicaña, JT Bell - Genome biology, 2021 - Springer
… have identified genetic variants as meQTLs for DNA methylation profiles. We also discuss
cellular mechanisms that may explain genetic impacts on DNA methylation levels. Lastly, we …

Differential methylation patterns from clusters associated with glucose metabolism: evidence from a Shanghai twin study

J Feng, Z Zhu, R Zhou, H Liu, Z Hu, F Wu, H Wang… - …, 2024 - Taylor & Francis
… As one of the most studied epigenetic modifications, DNA methylation (DNAm) occurring
almost exclusively at the 5′-cytosine-phosphate-guanine-3′ (CpG) site may be involved in …

Behavioral and biological divergence in monozygotic twin pairs discordant for autism phenotypes: A systematic review

L Myers, PY Pan, KL Remnélius, J Neufeld… - JCPP …, 2021 - Wiley Online Library
… Differential DNA methylation and gene expression were found among ASD discordant
twins; however, genetic results were inconsistent. Neurological disorders and early medical …

Socially stratified DNA-methylation profiles are associated with disparities in child and adolescent mental health

L Raffington, P Tanksley, L Vinnik, A Sabhlok… - medRxiv, 2021 - medrxiv.org
… First, we examined DNA-methylation profiles of a peripheral … Second, we examined genetic
profiles of inflammation (ie, … of salivary DNA-methylation data from the Texas Twin Project (N=…

Methylation status of VTRNA2-1/nc886 is stable across populations, monozygotic twin pairs and in majority of tissues

S Marttila, H Tamminen, S Rajić, PP Mishra… - …, 2022 - Taylor & Francis
… -origin-related DNA methylation pattern is created. For males, the DNA methylation profile of
the … For this study, 2423 individuals with DNA methylation data were included in the present …

[HTML][HTML] Methylation at CpG sites related to growth differentiation factor-15 was not prospectively associated with cardiovascular death in discordant monozygotic twins

SS Moore, P Mukherji, M Leung, CE Vrentas… - Scientific Reports, 2022 - nature.com
… in DNA methylation patterns between individuals is due to environmental factors, genetic
influences on DNA methylation are … those exhibiting high levels of variability in methylation 6 . …

Technical strategy for monozygotic twin discrimination by single-nucleotide variants

W Sun, Z Wang, S Wen, A Huang, H Li, L Jiang… - International Journal of …, 2024 - Springer
… Moreover, DNA methylation detection generally requires bisulfite treatment or enzymatic …
restrict the reliability of DNA methylation as a biomarker to distinguish between MZ twins. …