A comprehensive characterisation of phaeochromocytoma and paraganglioma tumours through histone protein profiling, DNA methylation and transcriptomic analysis …

P Chatzikyriakou, D Brempou, M Quinn, L Fishbein… - Clinical …, 2023 - Springer
… Herein, we report on global histone PTMs, DNA methylation and the transcriptomes of … (MS)
DNA methylation profiles of 52 PPGL tumours, and two normal adrenal medulla samples …

DNA methylation in stress and depression: from biomarker to therapeutics

AJ Sales, FS Guimarães, SRL Joca - Acta Neuropsychiatrica, 2021 - cambridge.org
… Stress and MDD are associated with hyperactivation of the hypothalamic–pituitary–adrenal
(… human and corticosterone in rodent) from the adrenal cortex into the blood. Glucocorticoids, …

Whole blood methylome-derived features to discriminate endocrine hypertension

R Armignacco, PS Reel, S Reel, A Jouinot, A Septier… - Clinical …, 2022 - Springer
identified blood DNA methylation loci associated with EHT. The blood DNA methylome profile
associated with the different … the identification of genes differentially methylated, such as …

Methylome analysis in nonfunctioning and GH-secreting pituitary adenomas

G Giuffrida, V D'Argenio, F Ferraù… - Frontiers in …, 2022 - frontiersin.org
… Whole-Genome DNA Methylation Sequencing The whole-genome DNA methylation profiling
of 11 GH-omas, 10 NFPAs, and 5 normal pituitaries was carried out with the TruSeq Methyl …

Global DNA methylation in suicidal ideation and suicide attempt in schizophrenia

A Bani-Fatemi, R Raymond, C Adanty, N Dai… - Psychiatric …, 2021 - journals.lww.com
… in SB comes from molecular studies of the hypothalamus-pituitary-adrenal (HPA) axis
genes. These studies have focused mainly on the glucocorticoid receptor and its trans-activator …

Paternal adverse childhood experiences: associations with infant DNA methylation

SM Merrill, SR Moore, N Gladish… - Developmental …, 2021 - Wiley Online Library
… One potential explanation suggests exposure to early adversity predicts epigenetic
modification, especially DNA methylation (DNAm), linked to later health. Stress experienced …

DNA methylation signatures as biomarkers of socioeconomic position

M Rajaprakash, LT Dean, M Palmore… - Environmental …, 2023 - academic.oup.com
This review article provides a framework for the use of deoxyribonucleic acid (DNA) methylation
(DNAm) biomarkers to study the biological embedding of socioeconomic position (SEP) …

[HTML][HTML] DNA methylation in polycystic ovary syndrome: emerging evidence and challenges

YN Liu, Y Qin, B Wu, H Peng, M Li, H Luo… - Reproductive Toxicology, 2022 - Elsevier
… Although the current research on DNA methylation in PCOS is not in-depth, it indicated …
DNA methylation and PCOS. It is expected to help accelerate the application of DNA methylation

Select early-life environmental exposures and DNA methylation in the placenta

M Mortillo, CJ Marsit - Current environmental health reports, 2023 - Springer
DNA methylation. One study assessed global placental DNA methylation based on PM 2.5
exposure during different time windows of pregnancy [38], observing an overall decrease in …

Discovery of molecular DNA methylation-based biomarkers through genome-wide analysis of response patterns to BCG for bladder cancer

D Ilijazi, W Pulverer, IE Ertl, U Lemberger, S Kimura… - Cells, 2020 - mdpi.com
… To characterize differences in DNA methylation profiles … [24], a DNA methylation microarray,
which interrogates more … to discover DNA methylation profiles that could help identify the …