… DNA methylation rolls in gene silencing and gastric cancer-related genes methylation.
Then… as an epigenetic markers and epigenetic treatments may be an efficient method for …

… able to interfere with emerging targets involved in cancer progression, as G-quadruplexes
or the epigenetic ones (eg: histone deacetylase, DNA and histones methyltransferase). The …

… FDA approval of various DNA methyltransferase inhibitors, collectively called DNA HMAs,
and histone deacetylase inhibitors (HDACi) has brought epigenetic therapy to the forefront of …

… Then, we selected 200 papers on inhibitors of DNA methylation and histone … of epigenetic
therapy in tumor treatment has focused largely on the opportunity to reprogram epigenetic …

… targeted therapy strategies for pancreatic cancer is of great importance. … and tumor cells
is abnormal DNA methylation, particularly hypermethylation of the promoter region of tumor …

… new insights into epigenetic therapies in clinical oncology, taking into account the crosstalk
between tumor epigenetics, … Thus, the primary biological functions of DNA methylation in the …

… treatment. Here, we enumerate and integratethe mechanisms of HDAC family members
in tumorigenesis and cancer progression, and address the new and exciting therapeutic …

… is the use of DNA methyltransferase inhibitors (DNMTis) and … , so their inhibition can be used
to enhance tumor suppressor … Epigenetic therapy appears to be a promising and beneficial …

… that epigenetic processes such as DNA methylation and … , diagnosis, and treatment of breast
cancer. These observations … aspects of existing epigenetic therapies in combination with …

… HDAC inhibitors generally contain hypermethylated DNA, indicating interference between the
histone acetylation/methylation and DNA methylation. … in normal and cancerous cells [144]. …