Closed-loop neuromodulation in an individual with treatment-resistant depression

KW Scangos, AN Khambhati, PM Daly, GS Makhoul… - Nature medicine, 2021 - nature.com
… We found that fluctuation in daily symptoms was significantly … activity correlate with emotion
states in humans 12 and VC/VS … Intracranial EEG and intracortical stimulation offer the rare …

[HTML][HTML] Personalized chronic adaptive deep brain stimulation outperforms conventional stimulation in Parkinson's disease

CR Oehrn, S Cernera, LH Hammer, M Shcherbakova… - medRxiv, 2023 - ncbi.nlm.nih.gov
… activities or to variations in severity of symptoms during daily life. … We found that medication
yielded the largest effect on … rodent models of parkinsonism 39 and in humans 21 , where it is …

[HTML][HTML] Benchmarking signal quality and spatiotemporal distribution of interictal spikes in prolonged human iEEG recordings using CorTec wireless brain interchange

AH Ayyoubi, B Fazli Besheli, MM Quach, JR Gavvala… - Scientific Reports, 2024 - nature.com
… deep brain stimulation (DBS) or responsive neurostimulation (… human intracranial EEG (iEEG)
using a benchtop version of the … of the BIC system to reliably detect interictal spikes with a …

Responsive neurostimulation as a treatment for super-refractory focal status epilepticus: a systematic review and case series

LD Ernst, AM Raslan, A Wabulya, HW Shin… - Journal of …, 2023 - thejns.org
… on topic, in English, and human studies, as well as the ref… subclinical and discovered
incidentally with intracranial EEG. … the time from day of RNS implantation to day of SE resolution …

[HTML][HTML] Seizure diaries and forecasting with wearables: epilepsy monitoring outside the clinic

BH Brinkmann, PJ Karoly, ES Nurse… - Frontiers in …, 2021 - frontiersin.org
… to ambulatory intracranial EEG, found vast discrepancies in … which will allow people with
epilepsy to plan daily activities and … Billeci et al. found that heart rate variability could be used to …

[HTML][HTML] Connectomics of human electrophysiology

S Sadaghiani, MJ Brookes, S Baillet - NeuroImage, 2022 - Elsevier
… the early detection of pathophysiological processes affecting brain … simultaneously with
fMRI and intracranial EEG). Note the … over the diurnal cycle. A related study using sensor-level …

[PDF][PDF] Changes in intracranial neurophysiology associated with acute COVID-19 infection

KK Sellers, N Stapper, DAA Maya, C Henderson… - Clinical …, 2023 - Elsevier
… observed a decrease in the number of daily detections (Fig. 1A-… the COVID-19 period, we
found a concurrent increase in low … Prior studies using scalp EEG have demonstrated gross …

Ambulatory EEG usefulness in epilepsy management

TF Hasan, WO Tatum IV - Journal of Clinical Neurophysiology, 2021 - journals.lww.com
… of initial human EEG recordings in 1924 as the EEG. Today, … were present on day 1 and day
2 on continuous EEG. He felt “… non-EEG seizure detection systems are capable of detecting

Closed-loop stimulation in periods with less epileptiform activity drives improved epilepsy outcomes

DN Anderson, CM Charlebois, EH Smith, TS Davis… - Brain, 2024 - academic.oup.com
found that most patients received stimulation between the rising phase and peak phase of
daily … In human patients implanted with intracranial electrodes, memory tasks—which rely on …

[HTML][HTML] Responsive Neurostimulation for Seizure Control: Current Status and Future Directions

U Boddeti, D McAfee, A Khan, M Bachani… - Biomedicines, 2022 - mdpi.com
… seizure detection in RNS, and the necessity to change RNS … human brain waves and
seizure patterns in patients with … in his/her seizure patterns on a given day. Therefore, efficacy …