Haematological consequences of acute uncomplicated falciparum malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data

WWARNF Haematology - BMC Med, 2022 - edoc.unibas.ch
… Background: Plasmodium falciparum malaria is associated … The risk of falling below 7 g/dL
in people who did not have … of uncomplicated falciparum malaria in Gabon. Wien Klin …

Development of molecular methods for screening Plasmodium infections: New diagnostics for the era of malaria elimination

A Lalremruata - 2021 - ub01.uni-tuebingen.de
… for microscopically detected non-falciparum or mixed species malaria in Gabon were … micro‑
scopically detected non‑falciparum or mixed species malaria in Gabon. Methods: Ultra‑deep …

Pharmacotherapy for artemisinin-resistant malaria

E Koehne, AA Adegnika, J Held… - Expert Opinion on …, 2021 - Taylor & Francis
… There is a fear of resistant Plasmodium falciparum emerging in … falciparum parasites with
decreased susceptibility/resistance … in Gabon in children with uncomplicated malaria reported a …

Mutations in Pfcrt and Pfmdr1 genes of Plasmodium falciparum isolates from two sites in Northcentral and Southwest Nigeria

CO Agomo, N Mishra, YA Olukosi, R Gupta… - Infection, Genetics and …, 2021 - Elsevier
… the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) gene and Plasmodium
falciparum multidrug resistance … , a significant decline in the early responses of childhood P. …

[HTML][HTML] Drug-induced hypersensitivity to artemisinin-based therapies for malaria

T Nordmann, S Borrmann, M Ramharter - Trends in Parasitology, 2022 - cell.com
… for uncomplicated Plasmodium falciparum malaria in virtually all … falciparum lineages within
South and Southeast Asia and … of decreasing therapeutic effectiveness, malaria cases and …

The problem of antimalarial resistance and its implications for drug discovery

TM Schäfer, L Pessanha de Carvalho… - Expert Opinion on …, 2024 - Taylor & Francis
… acquisition of drug resistance in Plasmodium falciparum is given. … responses showed a
decreased chloroquine uptake, leaving … while increasing susceptibility to mefloquine [Citation98]. …

Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre …

B Ogutu, A Yeka, S Kusemererwa… - The Lancet Infectious …, 2023 - thelancet.com
Background Emergence of drug resistance demands novel antimalarial drugs with new
mechanisms of action. We aimed to identify effective and well tolerated doses of ganaplacide …

Plasmodium falciparum population structure inferred by msp1 amplicon sequencing of parasites collected from febrile patients in Kenya

B Andika, V Mobegi, K Gathii, J Nyataya, N Maina… - Malaria Journal, 2023 - Springer
… This treatment was repeated every 48 h until > 98% of the parasites were in the early ring …
For unknown reasons, infections in Kisii declined to near zero by 2019. This is unlike in the …

Antimalarial treatment in infants

LC Kalkman, T Hanscheid, S Krishna… - Expert opinion on …, 2022 - Taylor & Francis
… , likely due to decreased peripheral perfusion resulting in decreased absorption rates [Citation47].
Specific age- or bodyweight-related PK differences were not observed [Citation48]. …

Drug repurposing: a review of old and new antibiotics for the treatment of malaria: identifying antibiotics with a fast onset of antiplasmodial action

L Pessanha de Carvalho, A Kreidenweiss, J Held - Molecules, 2021 - mdpi.com
… are Plasmodium falciparum (most prevalent in Africa) and P. … decreased parasite load and
suppressed malaria symptoms [… adults in Gabon, where the rate of chloroquine resistance is …