Decreasing trend of serum α-fetoprotein level in hepatocellular carcinoma
A Vipani, M Lauzon, M Luu, LR Roberts… - Clinical …, 2022 - cghjournal.org
Serum a-fetoprotein (AFP), a well-established biomarker for hepatocellular carcinoma
(HCC), increases the sensitivity of ultrasound-based surveillance programs for early stage
HCC detection. 1, 2 Multiple factors, including tumor burden, can affect AFP levels in
patients with HCC. 3 Nontumoral factors, such as race/ethnicity and liver disease etiology,
are also known to be associated with elevated AFP. 3 With the increasing trend of earlier
stage HCC detection and shift from viral to nonviral etiology, we hypothesized that AFP level …
(HCC), increases the sensitivity of ultrasound-based surveillance programs for early stage
HCC detection. 1, 2 Multiple factors, including tumor burden, can affect AFP levels in
patients with HCC. 3 Nontumoral factors, such as race/ethnicity and liver disease etiology,
are also known to be associated with elevated AFP. 3 With the increasing trend of earlier
stage HCC detection and shift from viral to nonviral etiology, we hypothesized that AFP level …
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