Antifungal liposomes directed by dectin-2 offer a promising therapeutic option for pulmonary aspergillosis
… Dectin-2-targeted delivery of amphotericin B to A. fumigatus resulted in remarkably higher
efficacy than that of the untargeted antifungal … various organs and show less nephrotoxicity or …
efficacy than that of the untargeted antifungal … various organs and show less nephrotoxicity or …
DectiSomes: glycan targeting of liposomal drugs improves the treatment of disseminated candidiasis
… , while improving the efficacy of various antifungal drugs would … -1 and Dectin-2 targeted
antifungal liposomes completely clear … Anidulafungin liposome nanoparticles exhibit antifungal …
antifungal liposomes completely clear … Anidulafungin liposome nanoparticles exhibit antifungal …
[HTML][HTML] Aiming for a bull's-eye: Targeting antifungals to fungi with dectin-decorated liposomes
… Our goal with DectiSomes is to dramatically improve the effectiveness of antifungal drugs by
… data show that Dectin targeting of liposomal AmB dramatically improves drug efficacy and …
… data show that Dectin targeting of liposomal AmB dramatically improves drug efficacy and …
DectiSomes: C-type lectin receptor-targeted liposomes as pan-antifungal drugs
… antifungal pipeline. DectiSomes represent a new drug delivery platform that enhances
antifungal efficacy … host toxicity for current and future antifungals. DectiSomes employ pathogen …
antifungal efficacy … host toxicity for current and future antifungals. DectiSomes employ pathogen …
[HTML][HTML] Targeted Delivery of Antifungal Liposomes to Rhizopus delemar
… delemar and their potential to enhance the efficacy of antifungal liposome treatment. … not
appear that AmB itself plays a measurable role in the enhanced efficacy of targeted liposomes. …
appear that AmB itself plays a measurable role in the enhanced efficacy of targeted liposomes. …
Antifungal therapy: Novel drug delivery strategies driven by new targets
S Wu, R Song, T Liu, C Li - Advanced Drug Delivery Reviews, 2023 - Elsevier
… of new antifungal agents or enhance the effectiveness of conventional … liposomes (Tuft-Lip)
exhibit improved macrophage absorption compared to unmodified liposomes and enhance …
exhibit improved macrophage absorption compared to unmodified liposomes and enhance …
[HTML][HTML] DC-SIGN targets amphotericin B-loaded liposomes to diverse pathogenic fungi
… Our goal herein was to show that targeting liposomal AmB … antifungal liposomes is a
continuation of our efforts to design DectiSomes for pan-antifungal therapies with increased efficacy […
continuation of our efforts to design DectiSomes for pan-antifungal therapies with increased efficacy […
Strategies of drug delivery for deep fungal infection: a review
Z Ma, X Wang, C Li - Pharmaceutical Nanotechnology, 2020 - ingentaconnect.com
… AmB liposomes (AmBLIP), the therapeutic efficacy of PEG-… the liposomal formulation of
fluconazole enhanced antifungal … unmodified liposomes, the OPM-coated formulation exhibited …
fluconazole enhanced antifungal … unmodified liposomes, the OPM-coated formulation exhibited …
Confronting antifungal resistance, tolerance, and persistence: advances in drug target discovery and delivery systems
L Chen, L Zhang, Y Xie, Y Wang, X Tian, W Fang… - Advanced Drug Delivery …, 2023 - Elsevier
… Moreover, novel drug delivery systems offer an another attractive option for the
development of effective antifungal therapies, as they can improve the efficacy and safety of …
development of effective antifungal therapies, as they can improve the efficacy and safety of …
Glabridin Inhibits Aspergillus fumigatus Growth and Alleviate Inflammation Mediated by Dectin-2 and NLRP3 Inflammasome
L Zhan, X Tian, J Lin, X Peng, G Zhao - Current Eye Research, 2023 - Taylor & Francis
… were exhibited to demonstrate the therapeutic efficiency of … amphotericin B-loaded
liposomes bound efficiently to some … Meanwhile, we explored the anti-fungal effect on different …
liposomes bound efficiently to some … Meanwhile, we explored the anti-fungal effect on different …