… Our study highlights that DBS effects can go beyond regularizing … The motor symptoms
of bradykinesia and rigidity are … a population of external globus pallidus (GPe) neurons that …

… pallidus, both pars externa and pars interna (GPe-GPi), and the thalamus. Parkinsonian …
in the basal ganglia by inducing a new regularized pattern of synchronous neuronal activity. …

… to alleviate its symptoms according to the development stage of PD. Deep brain stimulation
(… In contrast, we analyze the firing activity of neuronal populations via the Hodgkin–Huxley (…

… made on patients exhibiting a combination of bradykinesia and/or rigidity during the onset of
… The therapeutic mechanisms of DBS on neuronal activities is still not clear. Various studies …

… , giving rise to symptoms like bradykinesia, rigidity, and tremor. … the Vim is effective in
alleviating tremors, likely through … electrical subthalamic and pallidal stimulation enhances PD …

… STN DBS and levodopa alleviate some motor signs in parkinsonian mice. … In fact, one group
studying healthy NHPs has even observed positive modulation during movement in pallidal …

… pallidus externa (GPe), and substantia nigra pars reticular (SNr), and disrupted β band
oscillatory activity … Cell-specific high-rate STN optogenetic DBS alleviated pathologic circling and …

… , we stimulate the globus pallidus pars interna (GPi), globus … correlated with rest tremor,
bradykinesia, postural instability, gait … Deep brain stimulation (DBS) is a non-drug therapy for …

… typical motor symptoms such as bradykinesia, resting tremor, … the medial nucleus of the
globus pallidus (Gpi) have been … , dominance function and entropy regularization are used as …

… decreased spontaneous movement, bradykinesia, muscle rigidity, … types of pathogenesis
and alleviates PD symptoms through … of the subthalamic nucleus (STN) and the medial pallidus …