Enzyme commission number prediction and benchmarking with hierarchical dual-core multitask learning framework
… With the widespread adoption of high-throughput methods and high-quality infrastructure, …
for EC number prediction, we first introduced and evaluated the state-of-the-art deep learning …
for EC number prediction, we first introduced and evaluated the state-of-the-art deep learning …
[HTML][HTML] Deep learning-based kcat prediction enables improved enzyme-constrained model reconstruction
… a deep learning approach (DLKcat) for high-throughput k cat … the reliance on enzyme
commission (EC) number annotations to … formed the high-quality dataset for deep learning model …
commission (EC) number annotations to … formed the high-quality dataset for deep learning model …
Tools for computational design and high-throughput screening of therapeutic enzymes
… machine learning methods are being developed to improve catalytically potent enzymes
and predict … Machine learning (ML) enables the discovery of hidden patterns in abundant …
and predict … Machine learning (ML) enables the discovery of hidden patterns in abundant …
Evidential deep learning for trustworthy prediction of enzyme commission number
SR Han, M Park, S Kosaraju, JM Lee… - Briefings in …, 2024 - academic.oup.com
… high-throughput … allow one to enjoy the advantage of the protein structure-based approaches,
which can effectively identify the most similar folds and functional sites without high-quality …
which can effectively identify the most similar folds and functional sites without high-quality …
[HTML][HTML] Functional annotation of enzyme-encoding genes using deep learning with transformer layers
… Enzyme Commission (EC) number. Consequently, the ability to predict EC numbers could
substantially reduce the number … organisms and enabling metabolic engineering applications. …
substantially reduce the number … organisms and enabling metabolic engineering applications. …
Ecrecer: Enzyme commission number recommendation and benchmarking based on multiagent dual-core learning
… for accurately predicting EC numbers based on novel deep learning techniques. To … Deep
learning enables high-quality and high-throughput prediction of enzyme commission numbers…
learning enables high-quality and high-throughput prediction of enzyme commission numbers…
ProtEC: A Transformer Based Deep Learning System for Accurate Annotation of Enzyme Commission Numbers
… 9b04321 [30] JY Ryu, HU Kim, and SY Lee, “Deep learning enables highquality and high-throughput
prediction of enzyme commission numbers,” Proceedings of the National Academy …
prediction of enzyme commission numbers,” Proceedings of the National Academy …
Ultrahigh-Throughput Enzyme Engineering and Discovery in In Vitro Compartments
… next-generation sequencing and deep learning, strategies for … As long as high-quality enzymes
with sufficient specificity for … HT-MEK (high-throughput microfluidic enzyme kinetics) gave …
with sufficient specificity for … HT-MEK (high-throughput microfluidic enzyme kinetics) gave …
High-throughput prediction of enzyme promiscuity based on substrate–product pairs
H Xing, P Cai, D Liu, M Han, J Liu, Y Le… - Briefings in …, 2024 - academic.oup.com
… , and their outputs are typically Enzyme Commission (EC) or Kyoto … , enabling users to
curate candidate-enzyme libraries from any source. This method uses a deep neural network to …
curate candidate-enzyme libraries from any source. This method uses a deep neural network to …
Discovery of Toxin-Degrading Enzymes with Positive Unlabeled Deep Learning
D Zhang, H Xing, D Liu, M Han, P Cai, H Lin… - ACS …, 2024 - ACS Publications
… enable rapid and high-throughput identification of enzymes … of enzymes were selected
based on enzyme commission (EC) … relies on large-scale data to make high-quality predictions. …
based on enzyme commission (EC) … relies on large-scale data to make high-quality predictions. …