Prediction of Ovarian Cancer with Deep Machine Learning and Alternative Splicing

K Linder, R Watson, K Ulmer, D Bender… - Medical Research …, 2023 - esmed.org
… RNA-sequence data was then put into Deep-learning augmented RNA-seq analysis of
transcript splicing software suite… Deep-learning augmented RNA-seq analysis of transcript

Alternative splicing enhanced with deep machine learning: a novel method to detect ovarian cancer

SP Nobre, N Cardillo, E Devor, M McDonald… - Gynecologic …, 2021 - Elsevier
… (Deep-learning Augmented RNA-Seq) software suite. DARTS created a model of differential
alternative splicing … found 1,726 differentially spliced single exon transcripts between HGSC …

[HTML][HTML] Predicting splicing patterns from the transcription factor binding sites in the promoter with deep learning

TC Lin, CH Tsai, CK Shiau… - BMC …, 2024 - bmcgenomics.biomedcentral.com
RNA-seq data for 15 human tissues from the ENCODE data portal [25]. To obtain high quality
of data, the data … in any given paired tissues also augmented the datasets incrementally for …

A scoping review on deep learning for next-generation RNA-Seq. data analysis

D Pandey, P Onkara Perumal - Functional & Integrative Genomics, 2023 - Springer
… a special focus on determining novel transcripts, detecting and … data analysis adopting
deep learning–based algorithms for epigenetic modification, identification, extrapolation of splice

Generating bulk RNA-Seq gene expression data based on generative deep learning models and utilizing it for data augmentation

Y Wang, Q Chen, H Shao, R Zhang, H Shen - Computers in Biology and …, 2024 - Elsevier
… play a vital role in addressing issues such as novel gene discovery, detection of low-abundance
transcripts, construction of transcriptional landscapes [1], alternative splicing regulation, …

DeepRBP: A novel deep neural network for inferring splicing regulation

J Sancho Zamora, JA Ferrer-Bonsoms… - bioRxiv, 2024 - biorxiv.org
… Results: We present DeepRBP, a deep learning (DL) based … that predict splicing regulation
from bulk RNA-Seq data. In this … (or RBPTranscript) given bulk RNA-Seq data. DeepRBP is …

Explainable deep learning for augmentation of small RNA expression profiles

J Fiosina, M Fiosins, S Bonn - Journal of Computational Biology, 2020 - liebertpub.com
data sets. The relatively large number of high-quality samples allowed us to use DL for data
augmentation… information of potentially viral and bacterial transcripts (∼5600 contaminants), …

Verifying explainability of a deep learning tissue classifier trained on RNA-seq data

M Yap, RL Johnston, H Foley, S MacDonald… - Scientific reports, 2021 - nature.com
… it has been shown that gradual changes in transcript expression occur along the colon from
… have been more apparent if differential transcript splicing was taken into consideration 20 . …

DeepASmRNA: Reference-free prediction of alternative splicing events with a scalable and interpretable deep learning model

L Cao, Q Zhang, H Song, K Lin, E Pang - Iscience, 2022 - cell.com
spliced transcripts and classification of alternative splicing … method, AStrap, and other deep
learning models. Then, we … data and use an interpretation method to decipher splicing codes. …

A comprehensive benchmarking of differential splicing tools for RNA-seq analysis at the event level

M Jiang, S Zhang, H Yin, Z Zhuo… - Briefings in …, 2023 - academic.oup.com
… had no underlying biological meanings, so the deep-learning model DNN was not beneficial
(… Second, we removed all transcripts constituting the 1723 differential splicing events in the …