… glycolysis during inflammation, macrophages deficient for the … , NOD2 −/− mice may have
gut microbiome dysbiosis in both … from diet-induced metabolic disease including inflammation …

… sensors of peptidoglycan and regulators of key inflammatory … related to defects in NOD2
surveillance can lead to dysbiosis, … protein response, develop diet-induced insulin resistance. …

… major active component of the peptidoglycan motif, present in … and reduces inflammatory
and metabolic defects associated … gut dysbiosis-driven metabolic tissue inflammation and T2D …

… liver resident cells to promote inflammation and NAFLD. Little … Here, we showed that
NOD2-mediated peptidoglycan sensing … sensing within hepatocytes can influence diet-induced …

… mice also contributes to a state of metabolic inflammation in … Since adipose browning could
alleviate diet-induced obesity … Increased intestinal permeability induced by dysbiosis of gut …

… model of diet-induced stunting in conventional mice without small intestinal inflammation but
associated … mice in vivo, we used Nod2-deficient (Nod2 −/− ) mice and, as a control, mice …

… peptidoglycan may play a role in brain inflammation [53]. … in peptidoglycan biosynthesis
thereby restoring the dysbiosis in … diet-induced inflammation, dysbiosis, and insulin resistance,” …

… IL-18 levels, promotes gut dysbiosis and increases the risk of … , NLRP3 deficient mice exhibit
gut dysbiosis associated with … is an innate immunity receptor that recognizes peptidoglycan …

… sensing of bacterial cell wall components by brain neurons. In mice, we found that bacterial
peptidoglycan … deficiency leads to metabolic dysfunction in response to diet-induced obesity (…

… diet-induced obesity including a high fat diet (HFD). Consumption of HFD causes microbial
dysbiosis in … adipose tissue and hepatic inflammation, whereas NOD2 activators lower insulin …