[HTML][HTML] Lipid–protein and proteinprotein interactions in the pulmonary surfactant system and their role in lung homeostasis

O Cañadas, B Olmeda, A Alonso… - International journal of …, 2020 - mdpi.com
… and inadequate surfactant production. Thus, absence of CCT is cause of changes in surfactant
protein … Due to the role of hydrophilic proteins in lung immunomodulation, their absence …

Surfactant protein disorders in childhood interstitial lung disease

J Singh, A Jaffe, A Schultz, H Selvadurai - European Journal of Pediatrics, 2021 - Springer
… of surfactant protein deficiency in the context of chILD. … Surfactant is made up of 90%
phospholipids and 10% protein. … small hydrophobic proteins, while SP-A and SP-D are …

[HTML][HTML] Structural hallmarks of lung surfactant: Lipid-protein interactions, membrane structure and future challenges

JC Castillo-Sánchez, A Cruz, J Pérez-Gil - Archives of biochemistry and …, 2021 - Elsevier
… The shape of phospholipids with respect to its hydrophilic … of 35 residues (3.7 kDa) whose
deficiency is not lethal at birth … be mediated by the other hydrophobic surfactant protein, SP-B […

Recent progress on surfactant protein A: cellular function in lung and kidney disease development

SD King, SY Chen - American Journal of Physiology-Cell …, 2020 - journals.physiology.org
… with other surfactant proteins and phospholipids prevent … surfactant proteins (SP) B and C
and hydrophilic surfactant … SP-A genetic mutations or pulmonary surfactant deficiencies, with a …

[HTML][HTML] A recipe for a good clinical pulmonary surfactant

J Pérez-Gil - biomedical journal, 2022 - Elsevier
… amounts of the hydrophobic surfactant proteins, although … most abundant phospholipid
species in lung surfactant from … could originate a surfactant with defective performance, either …

[HTML][HTML] Anti-inflammatory and anti-viral actions of anionic pulmonary surfactant phospholipids

M Numata, DR Voelker - Biochimica et Biophysica Acta (BBA)-Molecular …, 2022 - Elsevier
… biophysical functions of pulmonary surfactant. Both hydrophobic proteins promote the
highly … The alteration of levels of pulmonary surfactant proteins and phospholipids in …

The biophysical function of pulmonary surfactant

SB Hall, YY Zuo - Biophysical Journal, 2024 - cell.com
… , which requires the hydrophobic surfactant protein SP-B, … Premature babies with
deficient surfactant injure the barrier … Phospholipids, which constitute approximately 92% (mol:mol…

[HTML][HTML] The role of pulmonary surfactants in the treatment of acute respiratory distress syndrome in COVID-19

S Wang, Z Li, X Wang, S Zhang, P Gao… - Frontiers in …, 2021 - frontiersin.org
… The proteins are of two types: hydrophilic and hydrophobic. … levels of surfactant proteins in
COVID-19 patients to delineate the association between surfactant deficiency and progression …

Pulmonary surfactant: a unique biomaterial with life-saving therapeutic applications

…, F Salomone, G Mazzola, D Amidani… - Current Medicinal …, 2022 - ingentaconnect.com
… ) of surfactant proteins and surfactant phospholipids are … discovery that small hydrophobic
surfactant proteins SP-B … in conditions other than primary surfactant deficiency, such as ARDS …

Revisiting the role of pulmonary surfactant in chronic inflammatory lung diseases and environmental exposure

N Milad, MC Morissette - European Respiratory Review, 2021 - Eur Respiratory Soc
… While the hydrophobic surfactant proteins SP-B and SP-C … phospholipid levels were
increased while surfactant proteinsSurfactant protein-A-deficient mice are susceptible to …