… regions of chromosome 3 that are also deleted … 3p21 are lost as a result of these deletions
(5, 7, 9, 16, 18). Other TSGs found in chromosomal regions commonly deleted in lung cancers …

… renal cell carcinoma (RCC), non-small cell lung cancer, and … transferred the truncated
chromosome 3 with deleted 3p21.3-… repressor gene(s) on the 3p21.3 chromosomal region may …

… by loss of the tumor suppressor gene(s) in the deleted allele; and … 3p21 and 3p24-3p26,
suggesting neither LOH of these 2 … region has been described as lung cancer tumor suppressor …

… , CGH) identified three common regions (3p14.2, 3p21.3 and 3p25… chromosomal 3p arm
deletion spans a large fraction of the arm including 3p14.2 region, the deletion of 3p14.2 region …

… m5C to oxidize it, which reverses DNA methylation (DNAm) to erase DNA methylation; thus,
this … in the altered microenvironment, mutagenesis, and increased chromosomal instability. …

… 3p21.3 region on human chromosome 3 (hChr.3), we used truncated hChr.3, which was
deleted from the 3p22 locus to the telomere region … cell cycle arrest in lung carcinoma cell line …

… To address this issue and to analyse the role of the different 3p regions involved in deletions,
we … of the presumed tumor suppressor gene at 3p21 involved in lung cancer development". …

… in non-small-cell lung cancer (21–23) and in colorectal cancer (24) but not in oral … at
3p21.31 in NE and TADE increased in the tumor. In addition, the size of a homozygous deletion of …

… Both GNA11 and STK11 are located on chromosome 19p13.3 and co-deletion of the two …
.3, is a tumor suppressor gene that is frequently mutated/deleted in lung adenocarcinoma [50]. …

… protein 1) (OMIM 603089), a tumor suppressor gene located on the 3p21.1 cytoband, is now
… gene and subsequent aggressiveness of the tumor. However, the minimal region of deletion …