… for the mutant allele, we derived two embryonic stem cell (ESC) … Although this does not rule
out all deletions, deletions of a few … a translocation would affect two or more chromosomes. …

… We assessed the impact of RT and/or TMZ on the somatic … We evaluated whole-genome
sequencing-derived mutational … This work extends our knowledge on the genomic response …

… To dissect the mechanisms by which 4C4 deletions influence PDAC phenotypes, we performed
RNA-… Analysis of an experimentally derived type I IFN response signature (Methods and …

… suppression, but deletion of the entire arm was necessary to … evaluated CN influence on
immune profiles and outcomes in … response and resistance to immunotherapy include deletion …

… genome editing can cause local DNA rearrangements and deletions up to several … , we did
not detect LOH that would be suggestive of chromothripsis in hematopoietic colonies derived …

… This condition is molecularly and clinically heterogeneous. Deletions involving two non-…
proximal (centromeric) critical regions, are sufficient to cause the majority of the recurrent clinical …

… The fate of duplicate genes and their impact to some … is operative in that deletion or mutation
of one member of a pair could have little impact on the organism compared to deletion or …

… cells, PSCs are programmed to die in response to genomic … base changes and small insertions
and deletions (indels) 21 , … their potential impact before research with a particular line is …

… deletion regions in the BBJ dataset: at FHIT on chromosome … , these results indicate a key
role of DNA damage-response … mortality outcomes (including cause of death), which were …

… guidelines, the PCR reaction should utilize sequence-tagged … can in fact cause confusion in
the interpretation of the results. … the best clinical outcomes for fertility, while deletions of AZFa…