… N-acetyl cysteine (NAC) when specifically delivered to activated … Dendrimer-mediated delivery
of NAC also avoids the … CD11b + microglial cells indicating that dendrimer-delivered NAC …

… microglial-targeted GLS inhibition in a mouse model of Rett syndrome (RTT), a developmental
disorder … elevated glutamatergic tone, upregulation of microglial GLS, oxidative stress and …

… Recently through the use of animal models of CA, microglia have … in survival in a mouse
model of Rett syndrome due to … data demonstrate that dendrimer-mediated delivery of NAC to …

… model for cerebral palsy, and was demonstrated to enable the normalization of reactive
microglia in several animal models … –Nacetyl cysteine conjugates in activated microglial cells. Int. …

… the abundant neuropeptide N-acetyl aspartylglutamate (NAAG… microglia, its activity is
significantly up-regulated in microglia … small and large animal models, and can deliver drugs to the …

… as microglia. An improvement in cognitive function in APPswe/PSEN1dE9 mouse models
was … As mentioned above, N-acetyl cysteine (NAC) has been considered as a neuroprotective …

… N-acetyl-l-cysteine (NAC), an antioxidant and anti-… Targeted delivery of therapeutics to
activated microglia in … NAC exhibits neuroprotective effects in animal models of chorioamnionitis …

… -PAMAM-OH)-N-acetyl-cysteine conjugate is currently being … Such an approach requires
delivery of the drug to microglia … to deliver drugs to microglia in many animal models after …

… , which hydrolyzes the neuropeptide to N-acetyl-aspartate and … , inflammatory preterm birth
injury, and Rett syndrome 13 , 14 , … Dendrimer-mediated drug delivery is particularly attractive …

… microglia and macrophages in regions of neuroinflammation in rodent models of cerebral
palsy, glioblastoma, Rett syndrome… an aggressive mouse model of amyloidosis; 5xFAD mice at …