A new series of antileukemic agents: Design, synthesis, in vitro and in silico evaluation of thiazole-based ABL1 kinase inhibitors

E Zeytün, MD Altıntop, B Sever… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
anticancer drugs that target kinases have been approved, and several promising candidates
are in various stages of clinical evaluation … to design and synthesize a large number of new

[HTML][HTML] Design, synthesis and docking studies of new hydrazinyl-thiazole derivatives as anticancer and antimicrobial agents

AM El-Naggar, A Zidan, EB Elkaeed… - Journal of Saudi …, 2022 - Elsevier
… contribution to the development of anticancer drugs because it is not only effective in the
treatment of diverse cancer types, but also acts as a cancer chemopreventive agents [16]. Also, …

Design, synthesis, anticancer evaluation and molecular docking studies of new imidazo [2, 1-b] thiazole -based chalcones

S Dadou, A Altay, M Koudad, B Türkmenoğlu… - Medicinal Chemistry …, 2022 - Springer
… exploitation towards the development of new anticancer agents, herein, we report the
synthesis and characterization of new imidazo[2,1-b]thiazole-based chalcones. Accordingly, the …

Synthesis and biological evaluation of thiazole and thiadiazole derivatives as potential anticancer agents

S Ekrek, S Şenkardeş, Ö Erdoğan… - Phosphorus, Sulfur, and …, 2023 - Taylor & Francis
… and thiazole based small molecules were designed and synthesized as potential anticancer
agents. Six … Our preclinical data show that these active compounds are potential therapeutic …

[HTML][HTML] Design, synthesis, in vitro biological assessment and in silico molecular modeling study of thiazole-thiazolidinone derivatives as potent anti-cancer agents

S Khan, H Ullah, R Hussain, MU Khan, Y Khan… - Results in …, 2024 - Elsevier
… through synthesis of highly effective therapeutic anticancer agents, … designed and synthesized
thiazole based thiazolidinone hybrid derivatives. The newly synthesized thiazole based

[HTML][HTML] Novel 1, 3-thiazole analogues with potent activity against breast cancer: A design, synthesis, in vitro, and in silico study

MG Salem, DMA El-Maaty, YIM El-Deen, BH Elesawy… - Molecules, 2022 - mdpi.com
… Additionally, several conservative systematic therapies are based on anticancer drugs, …
,3-thiazole-based compounds has attracted great attention to the design and synthesis of several …

Design, Synthesis and Biological Evaluation of a Novel Series of Thiadiazole-Based Anticancer Agents as Potent Angiogenesis Inhibitors

B Altuğ-Tasa, B Kaya-Çavuşoğlu… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
… this work was to design and synthesize thiadiazole-based anticancer agents with anti-an- …
anticancer agents. Bleomycine, dasatinib, and tiazofurin are thiazole-based anticancer agents, …

Synthetic and medicinal perspective of fused-thiazoles as anticancer agents

S Pawar, K Kumar, MK Gupta… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
… Thus, this review will definitely aid to develop a lead for the new selective anticancer
agents in future. … In this review, we will elaborate various types of fused thiazole as an …

Thiazole-based thiosemicarbazones: Synthesis, cytotoxicity evaluation and molecular docking study

SM Gomha, HA Abdelhady, DZH Hassain… - Drug design …, 2021 - Taylor & Francis
… synthetic thiazole compounds 1–17 could be used as potent inhibitors as anticancer drugs.
… as anticancer agents. Activity against anticancer cell lines would expect to show remarkable …

Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity

TA Farghaly, GS Masaret, ZA Muhammad… - Bioorganic chemistry, 2020 - Elsevier
… The crucial need for novel antitumor agents with high selectivity toward … to synthesize new
series of thiazole-based chalcones and 4-hetarylthiazoles (rigid chalcones). The synthesis of …