[HTML][HTML] Centrality of drug targets in protein networks

A Viacava Follis - BMC bioinformatics, 2021 - Springer
… We recognized that the network centrality features detected … depend on their hub position in
a scale-free network structure. … was derived from gene expression data rather than annotated …

[HTML][HTML] Identification of key gene modules and hub genes of human mantle cell lymphoma by coexpression network analysis

D Guo, H Wang, L Sun, S Liu, S Du, W Qiao, W Wang… - PeerJ, 2020 - peerj.com
… The use of gene expression analysis has been of interest, recently, to detect biomarkers for
… as illustrated by the topological overlap matrix (TOM) plot of 5,000 genes, suggesting that …

Graph2GO: a multi-modal attributed network embedding method for inferring protein functions

K Fan, Y Guan, Y Zhang - GigaScience, 2020 - academic.oup.com
Identifying protein functions is important for many biological … to compress graph structure
information and original node … features across the proteins based on the network structure, and …

[HTML][HTML] A protein interaction information-based generative model for enhancing gene clustering

P Dutta, S Saha, S Pai, A Kumar - Scientific Reports, 2020 - nature.com
… bioinformatics, identifying a set of genes which are … The user-specified structure of the
generative model directly impacts the … so that it can label the gene expression data efficiently. The …

[HTML][HTML] Weighted gene co-expression network analysis identifies specific modules and hub genes related to coronary artery disease

PF Zheng, LZ Chen, YZ Guan, P Liu - Scientific Reports, 2021 - nature.com
Analysis of network topology for various soft-thresholding … in disease detection or diagnosis
is particularly important for … Neural Network (CNN) to high-dimensional gene expression data

Identifying protein complexes from protein-protein interaction networks based on fuzzy clustering and GO semantic information

X Pan, L Hu, P Hu, ZH You - IEEE/ACM Transactions on …, 2021 - ieeexplore.ieee.org
… order to complete the task of identifying overlapping protein … consider both of the network
structure and GO, we observed … transcompel®: Transcriptional gene regulation in eukaryotes,…

Ontoprotein: Protein pretraining with gene ontology embedding

N Zhang, Z Bi, X Liang, S Cheng, H Hong… - arXiv preprint arXiv …, 2022 - arxiv.org
… makes use of structure in GO (Gene Ontology) into protein pre-training … of GO and its related
proteins, and gene annotation texts or … Since the relations in Gene Ontology are important for …

An effective link-based clustering algorithm for detecting overlapping protein complexes in protein-protein interaction networks

L Hu, J Zhang, X Pan, X Luo… - … Transactions on Network …, 2021 - ieeexplore.ieee.org
detect overlapping protein complexes. It first measures the similarity between pairwise
interactions from the perspectives of network topology and Gene Ontology. … form complete protein

Identification of signal pathways and hub genes of pulmonary arterial hypertension by bioinformatic analysis

RQ Wei, WM Zhang, Z Liang, C Piao… - Canadian Respiratory …, 2022 - Wiley Online Library
… effective tools to detect the gene expression differences between … Cytoscape software was
used to calculate the network topologicalnetwork for identifying hub genes in PAH. This PPI …

signatureSearch: environment for gene expression signature searching and functional interpretation

Y Duan, DS Evans, RA Miller, NJ Schork… - Nucleic acids …, 2020 - academic.oup.com
… all genes or proteins detected by the underlying expression … GESS-based rankings will
perfectly agree with structure-based … The columns contain: GO ontology a ; GO term description/ID …