… Cancer evolves through a process of somatic alterations [1], … changes can be detected by
multi-region sequencing (MRS). … Because multiple samples collected from a single tumor …

… patients rarely share recurrent mutations, … quick detection mode to determine the HPV types
and HPV-related reads to confirm whether the co-infection of multiple HPV existed in a tumor …

… SNVs) and 705 indels were detected in 41 NATs, which amounts … were detected in tumor
samples (Figure 1C), suggesting that … frequent driver events occurring at a different evolutionary …

… can help us to characterize the ITH of tumor tissue and … based on the evolutionary patterns
can help to detect the phenotype… evolution across multiple cancer types and revealed different …

… The median multi-region based tumor mutation burden (TMB) … on somatic mutations detected
in multiple regions. Figure 3a … The raw sequencing data generated in this study have been …

… -ITH tumors) with significant differences in multiple biological … Raw sequencing data of
E-MTAB-5905 was downloaded … , and thus may facilitate the development of acquired resistance [6…

… sequencing, obtained by sampling multiple regions of a single tumor (multi-region sequencing…
), where the non-synonymous mutations detected across all the regions are displayed in …

… We performed whole genome sequencing on 42 prostate cancer … We systematically collected
multiple samples as punches … of this clone and no copy number changes were detected. …

… a cancer evolution perspective. Hence, we aimed to perform … We systematically collected
multiple samples as punches … of this clone and no copy number changes were detected. …

… of 10 tumours with multi-region sampling. We show that … Raw sequencing data from the
tumour and normal samples … cancers where samples from multiple regions of the tumour …