Adverse drug events and medication relation extraction in electronic health records with ensemble deep learning methods

F Christopoulou, TT Tran, SK Sahu… - Journal of the …, 2020 - academic.oup.com
Identification of drugs, associated medication entities, and interactions among them are crucial
to prevent unwanted effects of drug therapy, known as adverse drug events. … medication-…

… study of the association between antipsychotic drugs and venous thromboembolism based on Food and Drug Administration Adverse Event Reporting System data

Y Yan, L Wang, Y Yuan, J Xu, Y Chen… - Expert Opinion on Drug …, 2024 - Taylor & Francis
… by antipsychotic drugs is one of the adverse drug reactions. … using data mining methods to
detect signals of drug-related … However, platelet aggregation mainly leads to arterial clots, not …

… -based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease

J Fang, P Zhang, Y Zhou, CW Chiang, J Tan, Y Hou… - Nature Aging, 2021 - nature.com
… The aggregation of Aβ protein is hypothesized to trigger a cascade of disease-causing …
However, anti-tau or anti-amyloid selective drug discovery approaches have a lack of clinical …

[HTML][HTML] SGLT-2 inhibitors and atrial fibrillation in the Food and Drug Administration adverse event reporting system

BM Bonora, E Raschi, A Avogaro, GP Fadini - Cardiovascular diabetology, 2021 - Springer
… normalization, unification, and ontological aggregation of the drugs, indications, and AE, …
among those for other ATC-A10 class drug was also detected after restricting to reports filed by …

Machine learning and data mining in manufacturing

A Dogan, D Birant - Expert Systems with Applications, 2021 - Elsevier
Manufacturing organizations need to use different kinds of techniques and tools in order to
fulfill their foundation goals. In this aspect, using machine learning (ML) and data mining (DM) …

[HTML][HTML] Spatiotemporal data mining: a survey on challenges and open problems

A Hamdi, K Shaban, A Erradi, A Mohamed… - Artificial Intelligence …, 2022 - Springer
detection, association and pattern mining, outlier detection, … , spatiotemporal discretisation
(or aggregation) is applied. The … point but requires the aggregation of the crimes occurred in …

Toward better drug discovery with knowledge graph

X Zeng, X Tu, Y Liu, X Fu, Y Su - Current opinion in structural biology, 2022 - Elsevier
… that implement drug repurposing and adverse drug reaction prediction for drug discovery.
As … are jointly propagated and updated in a recursive aggregation process. Feeney et al. [51] …

An integrated cluster detection, optimization, and interpretation approach for financial data

T Li, G Kou, Y Peng, SY Philip - IEEE transactions on …, 2021 - ieeexplore.ieee.org
… the most important ones and took negative effects, while the 5th feature … aggregation degree
of data points inside the cluster. Then, we designed an adaptive algorithm AdaEllip to detect

Open Targets Platform: supporting systematic drug–target identification and prioritisation

D Ochoa, A Hercules, M Carmona… - Nucleic acids …, 2021 - academic.oup.com
adverse drug reactions from the FDA Adverse Event Reporting System (FAERS) for approved
drugs, … provides more in-depth aggregation and analysis of data. Users can also rearrange …

A BIM-data mining integrated digital twin framework for advanced project management

Y Pan, L Zhang - Automation in Construction, 2021 - Elsevier
discovery of the process model by proper process mining … the distance of events to determine
behavior aggregation and abstraction… negative effects from potential bottlenecks if possible. …