Detection of Benzo [a] Pyrene Diol Epoxide-DNA Adducts in White Blood Cells of Asphalt Plant Workers in Syria

R Zohairee - Erythrocyte: A Peripheral Biomarker For Infection …, 2021 - books.google.com
… to lipids, protein and DNA to form BPDE adducts [20, 21]. These BPDE-DNA adducts can
result in … an asphalt worker and detection of BPDE-DNA adducts in the white blood cells (WBC), …

Serum albumin adducts, DNA adducts and micronuclei frequency measured in benzo [a] pyrene-exposed mice for estimation of genotoxic potency

HV Motwani, E Westberg, C Lindh… - … /Genetic Toxicology and …, 2020 - Elsevier
… Briefly, the whole blood was separated into red blood cells … , the exocyclic amino groups on
DNA, were detected by LC–MS/… of DNA adducts in the small amounts available from blood. In …

Intra and extracellular effects of benzo [α] pyrene on liver, gill and blood of Caspian White fish (Rutilus frissi kutum): Cyto-genotoxicity and histopathology approach

M Esmaeilbeigi, MR Kalbassi, J Seyedi… - Marine Pollution …, 2021 - Elsevier
… Moreover, the level of DNA damage in red blood cells of … repair enzymes and, in turn, an
increase of DNA adduct … and sensitive approach to detect the chromosome breakage and …

Genotoxic responses in blood

L Shugart - Nondestructive biomarkers in vertebrates, 2020 - taylorfrancis.com
… have been used to detect DNA adducts of a class of carcinogens such as benzo[a]pyrene,
benz[a]… Value reported based on 104 white blood cells per cubic millimeter blood. Use of …

Benzo[a]pyrene—Environmental Occurrence, Human Exposure, and Mechanisms of Toxicity

B Bukowska, K Mokra, J Michałowicz - International journal of molecular …, 2022 - mdpi.com
… [7] detected a higher level of BPDE protein adducts in … BPDE DNA adducts were also
determined in the placenta of … lower global DNA methylation in umbilical cord blood cells and that …

Benzo (a) pyrene-induced cytotoxicity, cell proliferation, DNA damage, and altered gene expression profiles in HT-29 human colon cancer cells

JN Myers, KL Harris, PV Rekhadevi, S Pratap… - Cell Biology and …, 2021 - Springer
… to DNA and the concentrations of BaP-DNA adducts. To … cells with B (a)P, DNA was isolated
from cells and DNA damage was assayed by the kit. No B(a)P-DNA adducts were detected

The relationship between exposure to airborne particulate and DNA adducts in blood cells in an urban population of subjects with an unhealthy body mass index

A Pulliero, S Iodice, AC Pesatori, L Vigna… - International Journal of …, 2022 - mdpi.com
… hydrocarbon), such as benzo(a)pyrene and benz(a)anthracene … adducts have been found
in the white blood cells of people … the ratio between cpm detected in DNA adducts and cpm in …

Hemoglobin adducts

LR Shugart - Nondestructive Biomarkers in Vertebrates, 2020 - taylorfrancis.com
… The detection of DNA adducts in environmental samples … millimeter of blood contains
over 106 red blood cells (varies … (0): Benzo[a]pyrene binding to DNA expressed as picogram …

Comet and Micronucleus Assays for Detecting Benzo (a) Pyrene Genotoxicity in Blood Cells of Nile Tilapia (Oreochromis niloticus) from the Shatt Al-Arab River in …

AN Al-Salman, A Ghaida'a Jassim… - Journal of …, 2022 - pnrjournal.com
… sensitive detection of both single and double strand breaks as well as the generation of
breaks at alkaline labile sites produced by DNA adduct creation. The high-sensitivity detection of …

[HTML][HTML] Enhanced DNA adduct formation by benzo [a] pyrene in human liver cells lacking cytochrome P450 oxidoreductase

L Reed, IWH Jarvis, DH Phillips, VM Arlt - Mutation Research/Genetic …, 2020 - Elsevier
… The nuclease P1 enrichment version of the thin-layer chromatography (TLC) 32 P-postlabelling
assay was used to detect DNA adducts as reported [14,24]. After chromatography, TLC …