Computational simulations of tumor growth and treatment response: Benefits of high-frequency, low-dose drug regimens and concurrent vascular normalization
… anti-angiogenic and anti-cancer drugs can decrease cancer … model of tumor growth,
angiogenesis, metabolism and drug … the discrete agents, such as tumor and endothelial cells, with …
angiogenesis, metabolism and drug … the discrete agents, such as tumor and endothelial cells, with …
Pathological angiogenesis: mechanisms and therapeutic strategies
AC Dudley, AW Griffioen - Angiogenesis, 2023 - Springer
… mechanisms and speculate how these processes may also be targeted with anti-angiogenic …
Endothelial cells (ECs) are the pivotal cells in vascular development, lining the surface of all …
Endothelial cells (ECs) are the pivotal cells in vascular development, lining the surface of all …
Cancer-associated angiogenesis: the endothelial cell as a checkpoint for immunological patrolling
… of antiangiogenetic drugs is crucial to inhibit the growth of … of tumor immune surveillance by
its ability to interact directly … normalized cancer oxygen delivery after tailored anti-angiogenic …
its ability to interact directly … normalized cancer oxygen delivery after tailored anti-angiogenic …
[HTML][HTML] … of αvβ3 integrin in 3D culture of triple-negative breast cancer and endothelial cells inhibits migration and discourages endothelial-to-mesenchymal plasticity
BC Casali, MP Baptista, BC Pachane, AA Cortez… - … and Biophysics Reports, 2024 - Elsevier
… of vascular endothelial growth factor (VEGF) overcoming … an initial step essential for
angiogenesis, we treated HUVEC … time the anti-angiogenic role of DisBa-01 in 3D cell culture, …
angiogenesis, we treated HUVEC … time the anti-angiogenic role of DisBa-01 in 3D cell culture, …
Microfluidics for angiogenesis research
L Costa, RL Reis, J Silva-Correia… - … Engineered 3D Models, 2020 - Springer
… angiogenesis, such as the vascular endothelial growth … ) an endothelial cell culture channel,
allowing the simultaneous application of different concentrations of the anti-angiogenic drug …
allowing the simultaneous application of different concentrations of the anti-angiogenic drug …
Angiogenesis and anti-angiogenic treatment in prostate cancer: mechanisms of action and molecular targets
E Ioannidou, M Moschetta, S Shah, JS Parker… - International journal of …, 2021 - mdpi.com
… trials, possibly leading to the development of new targeted anti-angiogenic therapies in PC.
… as tumor inhibitors [75]. They manage endothelial cells’ effects and angiogenesis in PC …
… as tumor inhibitors [75]. They manage endothelial cells’ effects and angiogenesis in PC …
KAI1 (CD82) is a key molecule to control angiogenesis and switch angiogenic milieu to quiescent state
JW Lee, J Hur, YW Kwon, CW Chae, JI Choi… - Journal of hematology & …, 2021 - Springer
… angiogenic growth factors. In this study, we identified a novel endogenous anti-angiogenic …
in suppressing metastasis and angiogenesis mainly in cancer cells and endothelial cells [4]. …
in suppressing metastasis and angiogenesis mainly in cancer cells and endothelial cells [4]. …
[HTML][HTML] Extracellular vesicles in tumor angiogenesis and resistance to anti‐angiogenic therapy
ZW Ye, ZL Yu, G Chen, J Jia - Cancer Science, 2023 - ncbi.nlm.nih.gov
… to endothelial cells (ECs) to promote tumor angiogenesis. … , several anti‐angiogenic drugs
have been developed and … Furthermore, VEGF 90k on the surface of EVs interacts well with …
have been developed and … Furthermore, VEGF 90k on the surface of EVs interacts well with …
[HTML][HTML] Tumor vessels as directors of the tumor microenvironment: new findings, current challenges & perspectives
… the development of anti-angiogenic therapies, … tumor angiogenesis. Additionally, far from
being incapable of genetic plasticity (as initially suggested by Folkman) tumor endothelial cells …
being incapable of genetic plasticity (as initially suggested by Folkman) tumor endothelial cells …
Validation of Human Bone Marrow-derived Mesenchymal Stem Cells and MCF-7 Breast Cancer Cells Co-culture Using a 3D Perfused Biomimetic Microfluidic …
AM Cimpean, S Comsa, A Sturza, AC Barb… - Anticancer …, 2024 - ar.iiarjournals.org
… platform for testing anti-tumor/anti-angiogenic drugs. … tumor growth through the process of
angiogenesis (9). The … to this experimental model, by replacing the endothelial cells with hBM-…
angiogenesis (9). The … to this experimental model, by replacing the endothelial cells with hBM-…