An eight-plex immunoassay for Group A streptococcus serology and vaccine development
AL Whitcombe, F Han, SM McAlister… - Journal of …, 2022 - Elsevier
… develop a multiplex beadbased immunoassay that can detect and quantify antibody responses
… Quantification of IgG antibodies and standardisation between assay runs was achieved …
… Quantification of IgG antibodies and standardisation between assay runs was achieved …
Development and Evaluation of a New Triplex Immunoassay That Detects Group A Streptococcus Antibodies for the Diagnosis of Rheumatic Fever
AL Whitcombe, P Hanson-Manful, S Jack… - Journal of Clinical …, 2020 - Am Soc Microbiol
… in antibody response. Accordingly, our objective was to … design and optimize the multiplex
immunoassay technology for the … Forty-five of these participants were excluded from analysis, …
immunoassay technology for the … Forty-five of these participants were excluded from analysis, …
Interlaboratory comparison of a multiplex immunoassay that measures human serum IgG antibodies against six-group B streptococcus polysaccharides
K Le Doare, MA Gaylord, AS Anderson… - Human Vaccines & …, 2024 - Taylor & Francis
… assay may be applied to vaccine development and could be used to … Luminex-based
immunoassay that was developed to quantify … The funders had no role in the design, analysis, or …
immunoassay that was developed to quantify … The funders had no role in the design, analysis, or …
Development and validation of a 6-plex Luminex-based assay for measuring human serum antibodies to group B streptococcus capsular polysaccharides
MA Gaylord, M Larrier… - Human Vaccines & …, 2024 - Taylor & Francis
… A multiplex direct Luminex-based immunoassay (dLIA) has been developed to … Citation32
was used for the validation study design and assay range determination for the 6-…
was used for the validation study design and assay range determination for the 6-…
Novel multiplex immunoassays for two important infectious diseases in Aotearoa New Zealand
AL Whitcombe - 2022 - researchspace.auckland.ac.nz
… -based multiplex immunoassays to study antibody responses … Multi-antigen analysis revealed
striking differences in the … thesis, where I developed a multiplex serological assay for SARS…
striking differences in the … thesis, where I developed a multiplex serological assay for SARS…
[HTML][HTML] Development and Characterisation of a Four-Plex Assay to Measure Streptococcus pyogenes Antigen-Specific IgG in Human Sera
… conserved in a global analysis of Strep A genomes [7]. … antibody responses elicited by
human Strep A vaccines in clinical trials and in seroepidemiological studies using a multiplexed …
human Strep A vaccines in clinical trials and in seroepidemiological studies using a multiplexed …
Development and validation of a sensitive and robust multiplex antigen capture assay to quantify streptococcus pneumoniae serotype-specific capsular …
G Rajam, Y Zhang, JM Antonello, RJ Grant-Klein… - Msphere, 2022 - Am Soc Microbiol
… the development, qualification, and clinical validation of a high-throughput and multiplex
ST-… ST-specific monoclonal antibodies for rapid and simultaneous quantification of the 15 STs …
ST-… ST-specific monoclonal antibodies for rapid and simultaneous quantification of the 15 STs …
Increased Breadth of Group A Streptococcus Antibody Responses in Children With Acute Rheumatic Fever Compared to Precursor Pharyngitis and Skin Infections
AL Whitcombe, R McGregor, J Bennett… - The Journal of …, 2022 - academic.oup.com
… Robust, high-throughput assays based on advanced multiplex … developed a triplex
immunoassay to measure antibody … syndromes, a focused analysis was performed on participants …
immunoassay to measure antibody … syndromes, a focused analysis was performed on participants …
[HTML][HTML] Multiplexed suspension array immunoassays for detection of antibodies to pneumococcal polysaccharide and conjugate vaccines
SA Dunbar - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
… This article reviews publications describing the development … the fluorescence of the
internal dyes allows distinct analysis … However, no significant effects on antibody response to …
internal dyes allows distinct analysis … However, no significant effects on antibody response to …
[HTML][HTML] Diagnosis of Streptococcus pneumoniae infection using circulating antibody secreting cells
… Analysis of the time course of the pathogen-specific IgG … with different patterns of antibody
responses to the four antigens (… Finally, we evaluated a multiplex Luminex assay to detect S. …
responses to the four antigens (… Finally, we evaluated a multiplex Luminex assay to detect S. …