The dynamic chromatin landscape and mechanisms of DNA methylation during mouse germ cell development

K Shirane - Genes & Genetic Systems, 2022 - jstage.jst.go.jp
… de novo DNAme in mouse germ cells as well as the … -existing patterns of DNAme from mother
cells to daughter cells (Fig. 1… -of-originDNAme in hybrid mouse embryos revealed that a sub…

[HTML][HTML] Aneuploidy and DNA methylation as mirrored features of early human embryo development

EN Tolmacheva, SA Vasilyev, IN Lebedev - Genes, 2020 - mdpi.com
… The methylation patterns of male germ cells are fully established … revealed gene-specific
hypermethylation. Aberrant … Remodeling the DNA methylation of an embryonic germ line

Embryo cryopreservation leads to sex-specific DNA methylation perturbations in both human and mouse placentas

S Mani, J Ghosh, EA Rhon-Calderon… - Human molecular …, 2022 - academic.oup.com
… have been closely examined by several laboratories in a gene-specificdevelopment, cell
cycle regulation and cell-matrix adhesion. Soon after … Mouse embryo collection and transfer …

DNA methylation establishment of CpG islands near maternally imprinted genes on chromosome 7 during mouse oocyte growth

QN Li, JY Ma, WB Liu, TG Meng, F Wang… - … and Development, 2020 - Wiley Online Library
DNA methylation imprinting is erased in early germ cells, … found that the dynamic methylation
patterns of various maternal … of methylation establishment in CpG islands is gene-specific. …

[HTML][HTML] Mammalian germ cell development: from mechanism to in vitro reconstitution

M Saitou - Stem Cell Reports, 2021 - cell.com
… between germ cells and somatic cells has naturally led to an assumption that germ cells
bear key … Bmp4 is required for the generation of primordial germ cells in the mouse embryo. …

Transdifferentiation occurs without resetting development-specific DNA methylation, a key determinant of full-function cell identity

A Radwan, J Eccleston, O Sabag, H Marcus… - Proceedings of the …, 2024 - pnas.org
… that reprogrammed cells struggle to change their original DNA methylation patterns. We …
In this study, we infected mouse embryonic fibroblasts (MEFs) with lentivirus carrying a Dox-…

DNA methylation changes induced by BDE-209 are related to DNA damage response and germ cell development in GC-2spd

X Li, Y Zhang, X Dong, G Zhou, Y Sang, L Gao… - Journal of …, 2021 - Elsevier
… epigenetic regulation in germ line development, we hypothesize … It is well known that gene
specific hypomethylation is … with the DNA methylation patterns of spermatogenic cell. This …

[HTML][HTML] Dynamic changes in whole genome DNA methylation, chromatin and gene expression during mouse lens differentiation

W Chang, Y Zhao, D Rayêe, Q Xie, M Suzuki… - Epigenetics & …, 2023 - Springer
methylation patterns associated with cellular differentiation. Identification of DNA methylation
patterns … Epigenetic mechanisms of eye and retinal development were examined through …

[HTML][HTML] Epigenetic regulation during primordial germ cell development and differentiation

NB Ramakrishna, K Murison, EA Miska… - Sexual Development, 2021 - karger.com
… repressive DNA methylation marks especially over germline-… cells), then mitotic-arrest (MA,
purple cells) fetal germ cells (… germ cell development, miRNA profiles in mouse fetal germ

[HTML][HTML] Role of transcription in imprint establishment in the male and female germ lines

J Liao, PE Szabó - Epigenomics, 2024 - Taylor & Francis
… by their monoallelic expression pattern from one parental … /3 in the germ cells before DNA
methylation can take place. The … , but not during early development or postnatal growth. …