[HTML][HTML] Developmental toxicity testing of unsubstituted and methylated 4-and 5-ring polycyclic aromatic hydrocarbons using the zebrafish embryotoxicity test
J Fang, S Dong, PJ Boogaard, IMCM Rietjens… - Toxicology In Vitro, 2022 - Elsevier
… decrease the potency to induce developmental toxicity, depending on the site of methyl
substituent. … system was used to evaluate the developmental toxicity potency of PAHs tested. The …
substituent. … system was used to evaluate the developmental toxicity potency of PAHs tested. The …
Use of new approach methodologies to study the developmental toxicity of polycyclic aromatic hydrocarbons
J Fang - 2023 - search.proquest.com
… developmental toxicity upon exposure to petroleum substances was tested in the present
thesis by testing the in vitro developmental toxicity … different developmental toxicity potencies of …
thesis by testing the in vitro developmental toxicity … different developmental toxicity potencies of …
Structure-based modeling to assess binding and endocrine disrupting potential of polycyclic aromatic hydrocarbons in Danio rerio
TL Souza, JZ da Luz, L dos Santos Barreto… - Chemico-Biological …, 2024 - Elsevier
… The results obtained from RMSD demonstrate the strength of the interactions between PAHs
and the proteins, as well as suggest their potential to act as possible endocrine disruptors in …
and the proteins, as well as suggest their potential to act as possible endocrine disruptors in …
Exploring the endocrine disrupting potential of a complex mixture of PAHs in the estrogen pathway in Oreochromis niloticus hepatocytes
TL de Souza, JZ da Luz, A de Almeida Roque… - Aquatic Toxicology, 2024 - Elsevier
… This study aimed to investigate the toxicity and endocrine disrupting potential of a
complex mixture of polycyclic aromatic hydrocarbons (PAHs) in the estrogen pathway using …
complex mixture of polycyclic aromatic hydrocarbons (PAHs) in the estrogen pathway using …
Recent advances in bioassays for assessing the toxicity of environmental contaminants in effect-directed analysis
Y Liu, M Li, QL Wan, X Wang, M Mortimer… - Journal of …, 2024 - Elsevier
… (PR), associated with endocrine disrupting effects, are widely used … for the monitoring of
developmental toxic effects caused by … toxicity tests are commonly used to detect developmental …
developmental toxic effects caused by … toxicity tests are commonly used to detect developmental …
Comparative analysis of neurotoxicity of six phthalates in zebrafish embryos
… are endocrine disruptors that dysregulate hormone synthesis, decrease steroid hormone
levels, and inhibit steroid hormone … Developmental toxicity testing was initially conducted to …
levels, and inhibit steroid hormone … Developmental toxicity testing was initially conducted to …
Current contamination status of traditional and emerging persistent toxic substances in the sediments of Ulsan Bay, South Korea
… The toxic potencies of these … and developmental toxicity were predicted, in addition to the
known mutagenicity. The potential mutagenicity, carcinogenicity, and developmental toxicity of …
known mutagenicity. The potential mutagenicity, carcinogenicity, and developmental toxicity of …
Modeling PAH Mixture Interactions in a Human In Vitro Organotypic Respiratory Model
… , immunotoxicity, reproductive toxicity, and developmental toxicity, … metabolism with high
efficacy and potency, and CYP1A1 was … toxicity metrics: retene, benzo[a]fluorene (BaF), benzo[b]…
efficacy and potency, and CYP1A1 was … toxicity metrics: retene, benzo[a]fluorene (BaF), benzo[b]…
[HTML][HTML] Characterization of polycyclic aromatic compounds in historically contaminated soil by targeted and non-targeted chemical analysis combined with in vitro …
IA Titaley, MM Lam, R Bülow, A Enell, K Wiberg… - Environmental …, 2021 - Elsevier
… be explained by 62 PACs with relative potency factors (REPs). The … , and 11H-benzo[b]fluorene
were tentatively identified in all … 4-azapyrene was only detected in S2 and dibenzo[a,c]…
were tentatively identified in all … 4-azapyrene was only detected in S2 and dibenzo[a,c]…
Comparative Analysis of Neurotoxicity of Six Phthalates in Zebrafish Embryos. Toxics 2021, 9, 5
CM Tran, TN Do, KT Kim - 2021 - search.proquest.com
… Developmental toxicity testing was initially conducted to determine sublethal concentrations
… Developmental toxicity and endocrine disrupting potency of 4-azapyrene, benzo[b]fluorene …
… Developmental toxicity and endocrine disrupting potency of 4-azapyrene, benzo[b]fluorene …