… decrease the potency to induce developmental toxicity, depending on the site of methyl
substituent. … system was used to evaluate the developmental toxicity potency of PAHs tested. The …

… developmental toxicity upon exposure to petroleum substances was tested in the present
thesis by testing the in vitro developmental toxicity … different developmental toxicity potencies of …

… The results obtained from RMSD demonstrate the strength of the interactions between PAHs
and the proteins, as well as suggest their potential to act as possible endocrine disruptors in …

… This study aimed to investigate the toxicity and endocrine disrupting potential of a
complex mixture of polycyclic aromatic hydrocarbons (PAHs) in the estrogen pathway using …

… (PR), associated with endocrine disrupting effects, are widely used … for the monitoring of
developmental toxic effects caused by … toxicity tests are commonly used to detect developmental …

… are endocrine disruptors that dysregulate hormone synthesis, decrease steroid hormone
levels, and inhibit steroid hormone … Developmental toxicity testing was initially conducted to …

… The toxic potencies of these … and developmental toxicity were predicted, in addition to the
known mutagenicity. The potential mutagenicity, carcinogenicity, and developmental toxicity of …

… , immunotoxicity, reproductive toxicity, and developmental toxicity, … metabolism with high
efficacy and potency, and CYP1A1 was … toxicity metrics: retene, benzo[a]fluorene (BaF), benzo[b]…

… be explained by 62 PACs with relative potency factors (REPs). The … , and 11H-benzo[b]fluorene
were tentatively identified in all … 4-azapyrene was only detected in S2 and dibenzo[a,c]…

… Developmental toxicity testing was initially conducted to determine sublethal concentrations
… Developmental toxicity and endocrine disrupting potency of 4-azapyrene, benzo[b]fluorene …