… NERD, but it is almost absent in patients with functional heartburn (FH), who are no more
considered … alterations can be the cause of increased heartburn perception, this has not been …

… heartburn and regurgitation. Considering the greater variation expected with PPI response
for extraesophageal symptoms, the diagnostic performance of empiric PPI trial for a diagnosis …

… Like PSWP, MNBI has been shown to increase diagnostic yield of pH testing as well as help
to distinguish NERD from functional heartburn [23]. In a prospective cohort analysis, MNBI …

… (a) and functional heartburn (b). Patients with reflux hypersensitivity have symptoms following
reflux episodes (green shading). Patients with functional heartburn have no esophageal …

… 17 Functional heartburn is characterized by reflux-related symptoms in the absence of
esophagitis at endoscopy, normal esophageal acid exposure during esophageal pH monitoring, …

… GERD diagnosis can be established with symptomatology, pathology, or physiology. … 4
Functional heartburn is defined as retrosternal burning discomfort or pain refractory to acid…

… functional heartburn [40, 41]. Heartburn is caused by an esophageal disorder other than
GERD… Conceivably, any inflammatory disorder of the esophagus might cause heartburn, but …

… (functional heartburn [ 86 ] and supragastric belching [ 85 ]). The study in patients with
functional heartburn … of life, and a trend for reduced heartburn catastrophizing [ 86 ]. The study in …

… between belching and heartburn was observed, presence of heartburn was significantly …
that belching with acid reflux causes heartburn in patients with non-erosive reflux diseases. …

… The prevalence of SGB and rumination in patients with RH was significantly higher than
in patients with functional heartburn (22%; P < .001). Patients with RH and rumination were …