Periprostatic adipose tissue thromboinflammation triggers prostatic neoplasia in early metabolic impairment: Interruption by rivaroxaban
I AlZaim, N El-Nikhely, A Al-Saidi, N Mougharbil… - Life Sciences, 2023 - Elsevier
… in genetically and diet-induced obesity animal models and to … ) levels as well as PAR1 and
PAR2 expression and activity [5]. … correlation between molecular changes in adipose tissue …
PAR2 expression and activity [5]. … correlation between molecular changes in adipose tissue …
[HTML][HTML] Orexins: A promising target to digestive cancers, inflammation, obesity and metabolism dysfunctions
A Couvineau, T Voisin, P Nicole, V Gratio… - World Journal of …, 2021 - ncbi.nlm.nih.gov
… -inflammatory effects were reverted by the SORA1 antagonist, … from diet-induced obesity
and improves glucose control[91]. … At the opposite exogenous OxA attenuates adiposity in rats …
and improves glucose control[91]. … At the opposite exogenous OxA attenuates adiposity in rats …
[HTML][HTML] Emerging novel targets for nonalcoholic fatty liver disease treatment: Evidence from recent basic studies
GY Wang, XY Zhang, CJ Wang… - World Journal of …, 2023 - ncbi.nlm.nih.gov
… Liver RIP3 deficiency can attenuate MCD diet-induced liver … of PAR2 with pepducin PZ-235,
a full antagonist of PAR2, not … by exercise, is also expressed in adipose tissue and the liver. …
a full antagonist of PAR2, not … by exercise, is also expressed in adipose tissue and the liver. …
[HTML][HTML] Thromboinflammatory processes at the nexus of metabolic dysfunction and prostate cancer: The emerging role of periprostatic adipose tissue
… in genetically induced and diet-induced obesity (DIO) animal … and attenuated AT macrophage
infiltration and inflammation [367]. … , PAR-2 antagonism in vivo may well impair adipocyte …
infiltration and inflammation [367]. … , PAR-2 antagonism in vivo may well impair adipocyte …
Soluble dipeptidyl peptidase-4 induces epithelial–mesenchymal transition through tumor growth factor-β receptor
CW Huang, SY Lee, CX Du, HC Ku - Pharmacological Reports, 2023 - Springer
… sDPP4 is correlated with metabolic syndrome. Because the … (PAR2), a G protein-coupled
receptor, is widely expressed in … cells were incubated with PAR2 receptor antagonist, GB83 (…
receptor, is widely expressed in … cells were incubated with PAR2 receptor antagonist, GB83 (…
4-octyl itaconate supplementation relieves soybean diet-induced liver inflammation and glycolipid metabolic disorders by activating the nrf2-pparγ Pathway in juvenile …
L Fu, H Liu, W Cai, D Han, X Zhu… - Journal of Agricultural …, 2021 - ACS Publications
… -induced liver inflammation, and it was demonstrated that OI could attenuate the expression
of … (44) The NADPH via PPP is the main reducing power required for fatty acid synthesis, and …
of … (44) The NADPH via PPP is the main reducing power required for fatty acid synthesis, and …
[PDF][PDF] Emerging roles of Protease-Activated Receptors in Cardiometabolic Disorders
D Fukuda - 2022 - repo.lib.tokushima-u.ac.jp
… by dabigatran attenuates endothelial dysfunction in diabetic … promotes diet-induced obesity
and adipose inflammation. Nat … the thrombin receptor antagonist in secondary prevention of …
and adipose inflammation. Nat … the thrombin receptor antagonist in secondary prevention of …
Upstream Regulators and Downstream Signals of YAP/TAZ in NAFLD
CJ Gao - 2023 - search.proquest.com
… αAR antagonist prazosin can attenuate liver inflammation [51]… /fructose (HFCF) diet-induced
steatohepatitis mouse model … In this thesis, we characterized PAR1 and PAR2 expression …
steatohepatitis mouse model … In this thesis, we characterized PAR1 and PAR2 expression …
[HTML][HTML] Soluble dipeptidyl peptidase-4 induces fibroblast activation through proteinase-activated receptor-2
SY Lee, ST Wu, YJ Liang, MJ Su, CW Huang… - Frontiers in …, 2020 - frontiersin.org
… of several disorders in addition to diabetes, such as obesity, … α-SMA expression (Asokananthan
et al., 2015). Our results demonstrated that the PAR2 antagonist or knocking down PAR2 …
et al., 2015). Our results demonstrated that the PAR2 antagonist or knocking down PAR2 …
[HTML][HTML] CD26/DPP4 as a therapeutic target in nonalcoholic steatohepatitis associated hepatocellular carcinoma
S Nishina, K Hino - Cancers, 2022 - mdpi.com
… CD26/DPP4 has been reported to attenuate anticancer … in vitro, generating an antagonistic
form that can engage its … adipocytes in white adipose tissue of diet-induced obese mice […
form that can engage its … adipocytes in white adipose tissue of diet-induced obese mice […