Xenobiotic metabolism and disposition
G Chen - An introduction to interdisciplinary toxicology, 2020 - Elsevier
… Xenobiotic chemicals can be hydrophilic or lipophilic. Hydrophilic chemicals are less absorbed
and more easily excreted … substrate selectivity are very different between FMOs and CYPs…
and more easily excreted … substrate selectivity are very different between FMOs and CYPs…
Ontogeny and cross-species comparison of pathways involved in drug absorption, distribution, metabolism, and excretion in neonates (review): kidney
R Bueters, A Bael, E Gasthuys, C Chen… - Drug Metabolism and …, 2020 - ASPET
… differences between species in maturation before and after birth. Absorption, distribution,
metabolism, and excretion … and maturation, which will lead to differences in toxicity and efficacy. …
metabolism, and excretion … and maturation, which will lead to differences in toxicity and efficacy. …
Xenobiotic transport and metabolism in the human brain
D Silva-Adaya, C Garza-Lombó, ME Gonsebatt - Neurotoxicology, 2021 - Elsevier
… the elimination of xenobiotic agents. In this review, we describe the different systems related
to the detoxification of xenobiotics in … The exit of different xenobiotics from the CNS generally …
to the detoxification of xenobiotics in … The exit of different xenobiotics from the CNS generally …
Xenobiotic metabolism and transport in Caenorhabditis elegans
JH Hartman, SJ Widmayer… - Journal of Toxicology …, 2021 - Taylor & Francis
… in more uptake of xenobiotics because of the difference in … to excrete xenobiotics, although
no apparent research has been done to address this. Similarly, transfer of xenobiotics from …
no apparent research has been done to address this. Similarly, transfer of xenobiotics from …
[HTML][HTML] The gut microbiome: an orchestrator of xenobiotic metabolism
SL Collins, AD Patterson - Acta Pharmaceutica Sinica B, 2020 - Elsevier
… host absorption and xenobiotic metabolism. Image 1 … to differences in drug metabolism
between individuals and … or endobiotics with small molecules to alter their excretion. The most …
between individuals and … or endobiotics with small molecules to alter their excretion. The most …
Drug metabolism
LA Stanley - Pharmacognosy, 2024 - Elsevier
… xenobiotic metabolism (in this chapter, the terms “xenobiotic … elimination and is the topic
of the remainder of this chapter. … and differences in drug bioavailability, even between …
of the remainder of this chapter. … and differences in drug bioavailability, even between …
The central role of cytochrome P450 in xenobiotic metabolism—a brief review on a fascinating enzyme family
F Esteves, J Rueff, M Kranendonk - Journal of xenobiotics, 2021 - mdpi.com
… of absorption, distribution, metabolism, and excretion (ADME… absortion, metabolism and
cellular excretion of xenobiotics, … shared among the same enzyme family and between different …
cellular excretion of xenobiotics, … shared among the same enzyme family and between different …
Chemical metabolism of xenobiotics by gut microbiota
R Nakov, T Velikova - Current Drug Metabolism, 2020 - ingentaconnect.com
… xenobiotic metabolites are further metabolized and excreted … specific xenobiotics but rather
that metabolism arises from … - and species-level variations in xenobiotic metabolism. When …
that metabolism arises from … - and species-level variations in xenobiotic metabolism. When …
Microphysiological systems in absorption, distribution, metabolism, and elimination sciences
KP Van Ness, F Cesar, CK Yeung… - Clinical and …, 2022 - Wiley Online Library
… the evaluation of cross-species differences in metabolism with compounds that have been
… by a circulating xenobiotic that is destined for renal excretion. Among the design attributes …
… by a circulating xenobiotic that is destined for renal excretion. Among the design attributes …
Plant pharmacology: Insights into in-planta kinetic and dynamic processes of xenobiotics
… to drugs in terms of drug absorption, distribution, metabolism and elimination (ADME). …
results of plant xenobiotic accumulation that enables comparison between methods, plants …
results of plant xenobiotic accumulation that enables comparison between methods, plants …