Estrogen regulates duodenal calcium absorption through differential role of estrogen receptor on calcium transport proteins

X Nie, H Jin, G Wen, J Xu, J An, X Liu, R Xie… - Digestive diseases and …, 2020 - Springer
… In this study, we demonstrate that ERα and ERβ exert differential actions … , intestinal calcium
absorption plays a crucial role in calcium homeostasis. Estrogen has wide biological effects

[HTML][HTML] Significance of G protein-coupled estrogen receptor in the pathophysiology of irritable bowel syndrome, inflammatory bowel diseases and colorectal cancer

D Jacenik, WM Krajewska - Frontiers in Endocrinology, 2020 - frontiersin.org
… In this review, we present the current state of knowledge about the contribution of the G
protein-coupled estrogen receptor to irritable bowel syndrome, inflammatory bowel diseases and …

[HTML][HTML] Role of estrogen receptors in health and disease

P Chen, B Li, L Ou-Yang - Frontiers in endocrinology, 2022 - frontiersin.org
… Tamoxifen can cause severe side effects in some tissues, such as … role of hormones in
gastrointestinal diseases. Considering the differential effects of ERs in different gastrointestinal

Targeting estrogen receptors in colorectal cancer

JW Maingi, S Tang, S Liu, W Ngenya, E Bao - Molecular Biology Reports, 2020 - Springer
… This review explores the recent findings on the therapeutic role of ERβ in … Estrogen receptors
alpha and beta exhibit differential tissue expression. Whereas ERβ is predominant in the gut

[HTML][HTML] G protein-coupled estrogen receptor in immune cells and its role in immune-related diseases

G Notas, M Kampa, E Castanas - Frontiers in endocrinology, 2020 - frontiersin.org
… a differential role of GPER1, compared to classical estrogen … to be downregulated in
Inflammatory Bowel Disease and … of a protective role of the receptor in bowel inflammation (81). …

[HTML][HTML] Differential effects of estrogen receptor alpha and beta on endogenous ligands of peroxisome proliferator-activated receptor gamma in papillary thyroid …

S Yang, Z Gong, Z Liu, M Wei, L Xue… - Frontiers in …, 2021 - frontiersin.org
role of ERα and ERβ on the production of endogenous peroxisome proliferator-activated
receptor … with an increased risk of bladder cancer and other side effects (5, 20, 21). Endogenous …

[HTML][HTML] Distribution and effects of estrogen receptors in prostate cancer: Associated molecular mechanisms

A Ramírez-de-Arellano, AL Pereira-Suárez… - Frontiers in …, 2022 - frontiersin.org
… used to carry their therapeutic effects of neoplastic in prostate … Its action may depend on
differential amounts of ERβ1 homo and … While the role of ERβ in PCa is well studied, there are …

[HTML][HTML] Estrogen receptor function: impact on the human endometrium

K Yu, ZY Huang, XL Xu, J Li, XW Fu… - Frontiers in …, 2022 - frontiersin.org
role of estrogen and its nuclear and membrane-associated … Moreover, the differential
effects of estrogen on endometrial cells … side effects observed with tamoxifen (151, 152). In …

[HTML][HTML] Estrogen receptors alpha and beta in acute myeloid leukemia

A Roma, PA Spagnuolo - Cancers, 2020 - mdpi.com
… the differential expression of ERα and ERβ subtypes can impact … stem cells and lung, colon,
mammary gland and prostate … The role of estrogen receptors in hematopoiesis and acute …

[HTML][HTML] Estrogen receptor β deficiency impairs gut microbiota: a possible mechanism of IBD-induced anxiety-like behavior

Y Ma, T Liu, X Li, A Kong, R Xiao, R Xie, J Gao, Z Wang… - Microbiome, 2022 - Springer
… Herein, we revealed the role of gut microbiota in the development of … differential gene
expressions in the hypothalamus, a key brain region involved in anxiety and stress, may contribute