… progestin dose, route of administration, formulation, combination with or without an estrogen,
and duration of use also contribute to different effects … due to different PR activation by each …

… receptors: progesterone receptors (PR) and androgen receptors (AR). Activation of these …
Although natural progesterone and testosterone have a therapeutic potential, their synthetic …

… Remarkably, progesterone shows a biphasic effect on p42 ERK activation, enhanc‑ ing
phospho‑p42 ERK levels five minutes after infusion and then reducing levels 15 min after infusion…

… physiological activation of AR by progesterone is well documented for humans, but less so
between different sperm subpopulations [53,57,60,63]. Our results indicate that progesterone …

… progesterone (PROG) and testosterone (T) into neuroactive metabolites. These metabolites
regulate myelination, brain maturation, neurotransmission, reproductive behavior and the …

… In other words, progesterone has different effects on gene expression when it is bound to …
, this does not imply that progesterone or progestins activate the receptor as a natural ligand …

… in rapid progesterone signaling via activation of inhibitory G proteins, thus lowering cAMP
production in human myometrial cells, as a means to alter progesterone action through …

… of different drug classes of synthetic estrogens, progestins… progesterone-like effects. They
may also interfere with estrogen and ARs, activating or blocking them, thus causing side effects…

… activation and induction of PRs in immune cells. The immunomodulatory effect of progesterone
is … comprise all substances that activate PR and result in progesterone-like effects, and …

… The reversal of endometrial hyperplasia by progestins is thought to occur through activation
of PRs, resulting in stromal decidualization and the subsequent thinning of the endometrial …