… VLA-4, a CD49d/CD29 heterodimer, are important factors in progenitor cell adhesion in bone
… Notably, we did not observe CD44-VLA-4 inside-out activation in normal CD34 + mobilized …

… bone marrow cells for 3 days followed by the activation with LPS and IFN-γ for 16 h, which
results in iNOS expression… -1 was co-expressed with CD62L and VLA-4, but not with lymph …

… Specifically, α4β1 (VLA-4), α5β1 (VLA-5), and αLβ2 (LFA-1) … that the CD34 + cord blood
HSCs expressing L-selectin form … the association of CXCR4 with the integrins VLA-4 and VLA-5. …

… of human hematopoietic stem and progenitor cells (HSPCs) from cord blood (CB), bone marrow
(BM… LFA-1 is mainly involved in the leukocyte adhesion cascade and also in the immune …

… -biased CD34+ precursors expressing more frequently LFA-1 and L-selectin and expressing
… receptors and adhesion molecules expressed by the progenitor cells, such as VLA-4, VLA-5…

… the bone marrow (BM) to PB also occur. Antigen-presenting … the HEVs and employ L-selectin
to interact with CD34 and Gly-… of LFA-1 and VLA-4, resulting in firm arrest. Effector CD8 + T …

… gene deletion in mice uncovered the contribution of VLA-4 in … of CD10 with upregulation
of L-selectin. Nat Immunol. 2012;… The chemokine SDF-1 activates the integrins LFA-1, VLA-4, …

… come into contact with the endothelial lining of the bone … α4β7, VLA-4, and LFA-1) bind
strongly to immunoglobulin cell … -1 activate the binding of CD34+ cell binding to the extracellular …

… ) fraction of cells enriched for stem and progenitor cells. These … However, based on CD34
and CD133 gene expression (… in CD34 pos HSCs, although the role L-selectin plays on these …

… -1 (PSGL-1) and L-selectin, causes loss of responsiveness to … integrin VLA-4 has been
described to be highly expressed … that a significantly enriched gene expression profile related to …