… of bone marrow leukemia progenitor cells out of total CD45 + … the integrins LFA-1 and
VLA-4 on CD34 + cells to bind their … Eph gene expression was low in the bone marrow of AML …

… , we have shown that VLA-4 and LFA-1 together are essential for … and Progenitor cells (HSPCs)
are a heterogeneous mixture … Finally, primary CD34 + HSPCs isolated from bone marrow …

… In contrast to integrin VLA-4, CD44 can interact with integrin … blood, and CD34 + hematopoietic
stem cells (HSCs). The … CD44 interacts with E- and L- selectin when it is sialo-fucosylated …

… LFA-1 (lymphocyte function-associated antigen-1; CD11a) on the HSPCs.35 HSPCs also
express several other adhesion molecules such as L-selectin … VLA-4 inhibitors lead to stem cell …

… the expression of the adhesion molecules L-selectin (CD62L)… function-associated antigen 1
(LFA-1), which play a key role … the expression of the adhesion molecules CD62L and VLA-4 (…

… progenitor cells and then become common lymphoid … -derived HOXA + CD34 +
progenitors—can efficiently differentiate into NK … VLA-4 mediates the recruitment of NK cells to the …

… -specific hematopoietic progenitor cells that interact via … superfamily such as VLA-4,
VLA-5, and LFA-1 which act as … , PSGL-1, and L-selectin with significant differences between …

… the capacity to engage E- and L-selectin [30]. In the context of … with VLA-4, which plays
a role in firm adhesion to endothelial … Two integrins, VLA-4 (α4β1 integrin) and LFA-1 (αLβ2 …

… CD34, GlyCAM-1 and MadCAM-1 87, 88 and that L-selectin-… an LFA-1 deficiency show
impaired immune cell infiltration in … blockade of LFA-1 and VLA-4 completely inhibits immune cell …

… As a result of the differential expression of chemokine receptors, … -4 (VLA-4), which binds to
vascular cell adhesion molecule-1 (… little L-selectin expression [18] and rely instead on LFA-1 …