Ellagic acid ameliorates lung damage in rats via modulating antioxidant activities, inhibitory effects on inflammatory mediators and apoptosis-inducing activities

A Aslan, YT Hussein, O Gok, S Beyaz, O Erman… - … Science and Pollution …, 2020 - Springer
… In the present study, we investigated the protective effect of ellagic acid against CCl 4 …
inhibitory effect on some inflammatory mediators (eg, NF-κB, TNF- α, COX-2, and regulatory effects

Ellagic acid protects Caco-2 cell monolayers against inflammation-induced permeabilization

DE Iglesias, E Cremonini, CG Fraga… - Free Radical Biology and …, 2020 - Elsevier
… to pro-inflammatory mediators, eg tumor … differentiated into an intestinal epithelial cell
monolayer were exposed to TNFα, as a clinically relevant and ubiquitous pro-inflammatory

Ellagic acid and urolithin A modulate the immune response in LPS-stimulated U937 monocytic cells and THP-1 differentiated macrophages

SB Rønning, V Voldvik, SK Bergum, K Aaby… - Food & function, 2020 - pubs.rsc.org
… , no effect could be observed with ellagic acid. In THP-1 cells, treatment with ellagic acid
dramatically reduced the expression of Toll-like receptor 4, while Uro A had no effect. The dual …

Ellagic acid inhibits neuroinflammation and cognitive impairment induced by lipopolysaccharides

GL Dornelles, JS de Oliveira, EJR de Almeida… - Neurochemical …, 2020 - Springer
… stimulates the production of pro-inflammatory mediators. This mechanism is apparently due
… This task consists of the spontaneous and differential exploration of familiar and new objects…

The punicalagin metabolites ellagic acid and urolithin a exert different strengthening and anti-inflammatory effects on tight junction-mediated intestinal barrier function …

NA Hering, J Luettig, B Jebautzke… - Frontiers in …, 2021 - frontiersin.org
… Within the present study, the impact of punicalagin, ellagic acid and urolithin A on
inflammation-induced barrier dysfunction was examined in the HT-29/B6 cell culture model, which is …

Ellagic acid prevents particulate matter-induced pulmonary inflammation and hyperactivity in mice: A pilot study

S Jeong, S Bae, EC Shin, JH Lee, JH Ha - International Journal of …, 2023 - mdpi.com
… C57BL/6 mice were orally pretreated with ellagic acid (EL; 20 mg/kg or EH; 100 mg/kg) for 7
… with or without ellagic acid pretreatment. All the cells in the BALF were stained with Diff-Quik …

Ellagic acid inhibits high glucose‑induced injury in rat mesangial cells via the PI3K/Akt/FOXO3a signaling pathway

W Lin, G Liu, X Kang, P Guo… - Experimental and …, 2021 - spandidos-publications.com
… secretion of inflammatory mediators, cytokines and growth factors and accelerate the
deterioration of renal function (31-33). A recent study has indicated that EA inhibited breast cancer …

Immunomodulatory; anti-inflammatory/antioxidant effects of polyphenols: a comparative review on the parental compounds and their metabolites

M Sobhani, MH Farzaei, S Kiani… - Food Reviews …, 2021 - Taylor & Francis
… Treg is a specialized subset of T lymphocyte differentiatedinhibitory effect with the highest
effect of protocatechuic acid. … hydrolysis produce ellagic acid, the gallic acid dimeric derivative…

The effects of Ellagic acid supplementation on neurotrophic, inflammation, and oxidative stress factors, and indoleamine 2, 3-dioxygenase gene expression in multiple …

G Hajiluian, SJ Karegar, F Shidfar, N Aryaeian… - Phytomedicine, 2023 - Elsevier
… The current study indicates that Ellagic acid intervention has a favorable effect on depression
in MS patients. This is achieved by reducing BDI-II scores, as well as levels of NO, cortisol, …

Ellagic acid as a tool to limit the diabetes burden: Updated evidence

AJ Amor, C Gómez-Guerrero, E Ortega, A Sala-Vila… - Antioxidants, 2020 - mdpi.com
… In this review we focus on ellagic acid (EA), a compound that can be … of polyphenols naturally
found in several fruits and seeds. There is increasing research on cardiometabolic effects