[HTML][HTML] The Fundamental Role of Oxime and Oxime Ether Moieties in Improving the Physicochemical and Anticancer Properties of Structurally Diverse Scaffolds
J Fotie, CM Matherne, JB Mather… - International Journal of …, 2023 - mdpi.com
… -based oximes and oxime ethers, derivatives of indirubin (5) … and synthesized a series of
indirubin-5-carboxamide oxime … of these oxime derivatives against drug-resistant cancer cell …
indirubin-5-carboxamide oxime … of these oxime derivatives against drug-resistant cancer cell …
2-Aminobenzothiazoles in anticancer drug design and discovery
G Huang, T Cierpicki, J Grembecka - Bioorganic Chemistry, 2023 - Elsevier
… based on their activities against tumor-related proteins, … Nitrogen/sulfur-containing heterocycles
are biologically … -aminobenzothiazole derivatives as new antineoplastic agents based on …
are biologically … -aminobenzothiazole derivatives as new antineoplastic agents based on …
[HTML][HTML] Research Progress on Structure and Anti-Gynecological Malignant Tumor of Shikonin
LN Ke, LQ Kong, HH Xu, QH Chen, Y Dong, B Li… - Frontiers in …, 2022 - frontiersin.org
… obtained sulfur-containing shikonin oxime has stronger anti-tumor … been synthesized artificially,
so screening or synthesis of … derivatives have synergistic sensitization effect on malignant …
so screening or synthesis of … derivatives have synergistic sensitization effect on malignant …
Discovery of benzochalcone derivative as a potential antigastric cancer agent targeting signal transducer and activator of transcription 3 (STAT3)
J Dong, J Yang, W Yu, H Li, M Cai, JL Xu… - Journal of Enzyme …, 2022 - Taylor & Francis
… Many synthetic and natural small molecules with various scaffolds have … , discovery of new
STAT3 inhibitors is still in an urgent demand. Interestingly, chalcone-containing derivatives …
STAT3 inhibitors is still in an urgent demand. Interestingly, chalcone-containing derivatives …
Synthesis and DFT calculations of metal(II) oxime complexes bearing cysteine as coligand and investigation of their biological evolutions in vitro and in silico
… applications in cancer therapy. Recent research has … in the discovery of new drugs,
improvement of existing drugs, and … 2022) of some oxime derivatives and their metal complexes. …
improvement of existing drugs, and … 2022) of some oxime derivatives and their metal complexes. …
Revisiting the Role of Sulfur based Compounds in monitoring of Various analytes through spectroscopical investigations
… , a newly designed and synthesized anthraquinone derivative, 2-(… sulfur-containing
luminescents. Figure 6A suggests a … research teams has also discovered and dsignated a series …
luminescents. Figure 6A suggests a … research teams has also discovered and dsignated a series …
Discovery of fast-acting dual-stage antimalarial agents by profiling pyridylvinylquinoline chemical space via copper catalyzed azide-alkyne cycloadditions
G Huang, CM Solano, J Melendez, S Yu-Alfonzo… - European journal of …, 2021 - Elsevier
… potential of 4-aminoquinoline and 1,2,3-triazole derivatives as mentioned above and in
conjugation with the potentially … -based antimalarial agents, we report the synthesis of a series of …
conjugation with the potentially … -based antimalarial agents, we report the synthesis of a series of …