Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

D Demontis, GB Walters, G Athanasiadis, R Walters… - Nature …, 2023 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
… , we discovered the first 12 genome-wide significant loci for ADHD 14 in a genome-wide

[HTML][HTML] Genome-wide analyses of attention deficit hyperactivity disorder identify 27 risk loci, refine the genetic architecture, and implicate several cognitive domains

D Demontis, GB Walters, G Athanasiadis… - Nature …, 2023 - ncbi.nlm.nih.gov
Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
… , we discovered the first 12 genome-wide significant loci for ADHD 14 in a genome-wide

[HTML][HTML] Translating discoveries in attention-deficit/hyperactivity disorder genomics to an outpatient child and adolescent psychiatric cohort

PJ Vuijk, J Martin, EB Braaten, G Genovese… - Journal of the American …, 2020 - Elsevier
… , a recent genome-wide association study (GWAS) 5 has, for the first time, … for significance
and replication. This groundbreaking analysis 5 revealed 12 genome-wide significant loci, …

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

D Demontis, GB Walters, G Athanasiadis, R Walters… - MedRxiv, 2022 - medrxiv.org
Attention deficit hyperactivity disorder (ADHD) is a prevalent childhood psychiatric disorder,
… We fine-map identified risk loci and integrate our results with functional genomics data to …

Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder

KS O'Connell, A Shadrin, S Bahrami, OB Smeland… - Molecular …, 2021 - nature.com
… jointly associated with attention deficit/hyperactivity disorder (… was supported by significant
positive genome-wide genetic … novel risk loci for ADHD (Table 1) and 40 novel risk loci for …

Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder

D Demontis, RK Walters, VM Rajagopal… - Nature …, 2021 - nature.com
… identify three genome-wide significant loci on chromosomes 1, 7, and 11. A meta-analysis
including a Chinese cohort supports that the locus on chromosome 11 is a strong risk locus for …

Insights into attention-deficit/hyperactivity disorder from recent genetic studies

I Brikell, C Burton, NR Mota, J Martin - Psychological medicine, 2021 - cambridge.org
… review focuses on more recent genome-wide studies. Initial ADHD … As more ADHD risk loci
are discovered, methods will be … -genetic risk factors in attention deficit hyperactivity disorder. …

Druggable genome in attention deficit/hyperactivity disorder and its co-morbid conditions. New avenues for treatment

TA Hegvik, K Waløen, SK Pandey, SV Faraone… - Molecular …, 2021 - nature.com
Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder
with only symptomatic care available. Genome-wideAttention deficit/hyperactivity disorder (…

Polygenic risk score analysis revealed shared genetic background in attention deficit hyperactivity disorder and narcolepsy

N Takahashi, T Nishimura, T Harada… - Translational …, 2020 - nature.com
… previously collected genome-wide association study of narcolepsy and EHS, we calculated
polygenic risk scores … ADHD attention deficit hyperactivity disorder, PRS polygenic risk score. …

Genome guided personalized drug therapy in attention deficit hyperactivity disorder

J Haavik - Frontiers in Psychiatry, 2022 - frontiersin.org
… The first conclusively genome wide significant findings only emerged after the inclusion of
… of genetic risk factors, with some major risk loci in combination multiple other loci of small …