… of modulation of transporter expression and/or function in the … their impact on pharmacokinetics
(PKs), drug–drug interactions (… changes in pediatric patients may alter systemic and/or …

… transporters could affect the pharmacokinetics of many drugs… substrates or inhibitors of the
drug transporters. Here, we review … potential substrates and/or inhibitors of transporters by the …

… and Alzheimer disease) may affect drug transporter expression and … content may not only
affect pharmacokinetics of its drug … are derived from in vitro and/or animal studies, and should …

… uptake carriers and/or efflux transporters may lead to reduced drug … may mediate altered
drug pharmacokinetics, drug–drug … disease affects expression and function of drug carriers and …

… , 7 physiologically based pharmacokinetic (PBPK) modeling … carbamazepine with drug
transporter substrates can result in … Direct regulation of human drug transporters (mRNA and/or …

… condition shared by numerous chronic diseases. In addition, … drugs that affect DMETs are
well-known variables that can … exposure and/or pharmacokinetic parameters of the main drugs …

… Drugs can elicit folate deficiency by interfering with folate metabolism and/or transport (eg, …
affects celiprolol pharmacokinetics (PK) at the therapeutic dose. However, in vitro …

… drugs may reach the CNS by passive diffusion or be subjected to putative influx and/or efflux
through BBB membrane transporters… transport of drugs impacting their pharmacokinetics [46]…

… the pharmacokinetic parameters affected by changes in drug … affinity to albumin can impact
free drug concentrations. Free … in an increased efficacy of the drug and/or increase the risk of …

… P-gp-mediated drug transport might result in increased oral … -related low plasma albumin,
conformational change of the … , and/or drug metabolites competing with the acidic drugs for …