… Changes of the cerebral vasculature are triggered and driven by systemic vascular abnormalities
that are part of aging, and … the dissection of disease mechanisms underlying vascular …

… role of age-related vascular factors in the mechanisms of AD (4). This review will address the
vascular changes … the unprecedented opportunity to dissect the cellular crosstalk underling …

… translated to different tissues to dissect the specific role played by cells, circulating molecules,
and biophysical stimuli during physiological vascular aging and pathological remodeling. …

… -β clearance through the brain vasculature 11 , and the … revealed many functional changes
associated with ageing, as … Highlighting the importance of glia–vasculature cell interactions…

… Another study using laser dissection microscopy assisted quantitative mass spectrometry …
changes to the cerebrovascular proteome may explain the vascular contribution of aging and …

… pathologies, and that vascular changes are intimately related … , 25 mg of tissue was dissected
before nuclei isolation. Tissue … , CAA, aging, and small vessel disease and compared them …

… vascular and neurodegenerative pathological changes [9]. … circulation, vascular mural
cells play a critical role in cerebral … by diabetes and hypertension during aging [95]. Fibrinoid …

… in aging and diabetes. One of the pathways by which arteriolosclerosis may contribute to
dementia is via small microinfarcts in the aging … to generate SVD-like arterial changes in rats or …

… hypothesis that vascular changes in the brain may play a role in … The role of NfL in dissecting
the contribution of amyloidosis … SVD is a common accompaniment of ageing and frequently …

… CBF, and altered hippocampal vasoreactivity that contributed to their behavioral … changes
have not been fully elucidated. As the vascular and two-hit hypothesis for AD stipulate, aging…