Mathematical modelling of drug release

A Elmas, G Akyüz, A Bergal, M Andaç… - Research on …, 2020 - avesis.omu.edu.tr
… solubility in the ointment base faster than the diffusion speed of the dissolved drug particles
there. This assumption is important because diffused particle is immediately replaced by the …

[HTML][HTML] In vitro drug release, permeability, and structural test of ciprofloxacin-loaded nanofibers

LÉ Uhljar, SY Kan, N Radacsi, V Koutsos… - Pharmaceutics, 2021 - mdpi.com
… higher dissolution rate than … drug release than the physical mixture (p < 0.05) in time points
at 5 and 10 min. Besides, while all the samples showed fast dissolution behavior, the release

Patterns of drug release as a function of drug loading from amorphous solid dispersions: A comparison of five different polymers.

S Saboo, DE Moseson, US Kestur, LS Taylor - European Journal of …, 2020 - Elsevier
… loading ASDs (≤10% DL) in this study, irrespective of polymer type, drug and polymer
release congruently with the dissolving tablet surface retaining its initial homogeneous …

[HTML][HTML] Progress of electrospun nanofibrous carriers for modifications to drug release profiles

Y Wang, DG Yu, Y Liu, YN Liu - Journal of Functional Biomaterials, 2022 - mdpi.com
… Therefore, the controlled-release effect and drug dissolution enhancement can be achieved
through polymer properties (such as degree of polymerization and degree of hydrolysis), …

[HTML][HTML] Drug release study of the chitosan-based nanoparticles

Y Herdiana, N Wathoni, S Shamsuddin, M Muchtaridi - Heliyon, 2022 - cell.com
drug release properties and kinetics of the drug release model. Kinetic models help describe
the release … , optimizing the drug delivery device's design, evaluating the drug release rate, …

[HTML][HTML] Mechanism of a long-term controlled drug release system based on simple blended electrospun fibers

J Wu, Z Zhang, W Zhou, X Liang, G Zhou… - … of Controlled Release, 2020 - Elsevier
drug release profiles can be divided into three stages according to the rate of drug release.
… the rate of PEG release also decreased, indicating that PEG dissolution was caused by fiber …

Hyaluronic acid thiol modified injectable hydrogel: Synthesis, characterization, drug release, cellular drug uptake and anticancer activity

K Xu, H Yao, D Fan, L Zhou, S Wei - Carbohydrate Polymers, 2021 - Elsevier
… Thus, during the above crosslink process, the dissolved drug in DMSO could be effectively
loaded inside the hydrogels' porous structures as an injectable peritumoral implant. The …

Engineered spindles of little molecules around electrospun nanofibers for biphasic drug release

H He, M Wu, J Zhu, Y Yang, R Ge, DG Yu - Advanced Fiber Materials, 2021 - Springer
drug release is a popular advanced drug controlled release … strong platform for developing
biphasic release dosage forms. In this … In vitro drug dissolution tests: a drug release profiles of …

[HTML][HTML] Fabrication of tri-layered electrospun polycaprolactone mats with improved sustained drug release profile

SM Kamath, K Sridhar, D Jaison, V Gopinath… - Scientific Reports, 2020 - nature.com
… Moreover, poorly water soluble drugs like carvedilol and IBU loaded into PCL nanofibrous …
in dissolution 12 . To overcome the problem of dissolution and release of poor drug releasing

3D printed bilayer tablet with dual controlled drug release for tuberculosis treatment

AG Tabriz, U Nandi, AP Hurt, HW Hui, S Karki… - International Journal of …, 2021 - Elsevier
drug degradation and assure consistent deposition of drug-… The in-vitro drug release rate
was optimised by varying drug … to dissolution medium, thus, exhibited a fast drug release, ie …