… of clinicopathologic and molecular tumor features with recurrence in resected early-stage epidermal growth factor receptor–positive nonsmall cell lung cancer

SPL Saw, S Zhou, J Chen, G Lai, MK Ang… - JAMA Network …, 2021 - jamanetwork.com
… increased recurrence risk among patients with EGFR-positive NSCLC and distinct from
wildtype EGFR NSCLC. To this end, we developed an individual patient nomogram of routine …

[HTML][HTML] … expression, immune microenvironments, and clinical outcomes in epidermal growth factor receptor mutant lung adenocarcinoma patients treated with tyrosine …

CY Yang, WY Liao, CC Ho, KY Chen, TH Tsai… - … journal of cancer, 2020 - Elsevier
… pre-treatment PD-L1 might be used to categorize different … , leading to distinct clinical
outcomes and varied potentials to … first-line treatment of advanced non-small-cell lung cancer with …

Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC)

C O'Leary, H Gasper, KB Sahin, M Tang, A Kulasinghe… - Pharmaceuticals, 2020 - mdpi.com
… This has led to superior patient outcomes when used as a monotherapy over traditional …
This agent was evaluated in phase III studies in two different settings: initially, in second-line …

Genomic alterations and clinical outcomes in patients with lung adenocarcinoma with transformation to small cell lung cancer after treatment with EGFR tyrosine …

W Wang, C Xu, H Chen, J Jia, L Wang, H Feng… - Lung Cancer, 2021 - Elsevier
epidermal growth factor receptor (EGFR)-TKI treatment … into non-small cell lung cancer
(NSCLC) and small cell lung … Baseline characteristics were stratified according to different-…

[HTML][HTML] Comparative clinical outcomes for patients with advanced NSCLC harboring EGFR exon 20 insertion mutations and common EGFR mutations

L Bazhenova, A Minchom, S Viteri, JM Bauml, SHI Ou… - Lung Cancer, 2021 - Elsevier
Non-small cell lung cancer … mutations in the epidermal growth factor receptor (EGFR) gene,
treatment with EGFR … or treated outside the Flatiron network could have different outcomes. …

First‐line treatment of advanced epidermal growth factor receptor (EGFR) mutation positive non‐squamous nonsmall cell lung cancer

J Greenhalgh, A Boland, V Bates… - Cochrane Database …, 2021 - cochranelibrary.com
… If in future versions of this review we identify trials comparing different interventions that
are similar enough in their populations and outcomes, we may make indirect comparisons for …

Worldwide prevalence of epidermal growth factor receptor mutations in non-small cell lung cancer: a meta-analysis

B Melosky, K Kambartel, M Haentschel… - Molecular Diagnosis & …, 2022 - Springer
… Our study was unique in that it also examined the prevalence of the most prominent TKI-sensitizing
submutations. Although there were regional differences in the distribution of …

[HTML][HTML] Prognostic value of epidermal growth factor receptor gene mutation in resected lung adenocarcinoma

C Deng, Y Zhang, Z Ma, F Fu, L Deng, Y Li… - The Journal of thoracic …, 2021 - Elsevier
… After surgery, distinct metastatic patterns were revealed according to EGFR mutation status.
… and KRAS mutations on clinical outcome in resected non-small cell lung cancer patients

A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer

V Subramaniyan, S Fuloria, G Gupta, DH Kumar… - Chemico-biological …, 2022 - Elsevier
Epithelial growth factor receptor (EGFR) is a cell surface … the extracellular messages inside
the cell and thereby alter the … to most advanced clinical studies with different combination …

The significance of epidermal growth factor receptor uncommon mutations in non-small cell lung cancer: A systematic review and critical appraisal

V Gristina, U Malapelle, A Galvano, P Pisapia… - Cancer Treatment …, 2020 - Elsevier
… In addition, with the introduction of different NGS gene approach an improvement of EGFR
patients with these mutations from the analysis to define the clinical outcome (LUX-Lung 2, 3 …