Therapeutic implications of miRNAs for muscle-wasting conditions

L Yedigaryan, M Sampaolesi - Cells, 2021 - mdpi.com
… Myotonic dystrophy is characterized by progressive myotonia, muscle weakness, and
multiorgan involvement. There are two distinct types of myotonic dystrophy: myotonic dystrophy …

Dysregulation of muscle-specific MicroRNAs as common pathogenic feature associated with muscle atrophy in ALS, SMA and SBMA: evidence from animal models …

C Malacarne, M Galbiati, E Giagnorio… - International journal of …, 2021 - mdpi.com
neuromuscular disorder characterized by selective loss of the brainstem and spinal motor
neurons, leading to progressive … fluids and may reflect distinct pathophysiological states, they …

Role of microRNA in muscle regeneration and diseases related to muscle dysfunction in atrophy, cachexia, osteoporosis, and osteoarthritis

J Brzeszczyńska, F Brzeszczyński… - Bone & joint …, 2020 - boneandjoint.org.uk
… Impaired musculoskeletal homeostasis leads to distinct muscle atrophies. Understanding …
miRNA expression in muscle of septic ICU patients, which reported an increase in primary miR-…

Longitudinal study of three microRNAs in Duchenne muscular dystrophy and Becker muscular dystrophy

S Trifunov, D Natera-de Benito… - Frontiers in …, 2020 - frontiersin.org
… treatment on microRNAs expression. We measure the … progressive degenerative disorder
we investigated if circulating … % specificity and sensitivity in distinguishing between DMD and …

MicroRNA and mRNA profiling in the idiopathic inflammatory myopathies

JE Parkes, A Thoma, AP Lightfoot, PJ Day, H Chinoy… - BMC rheumatology, 2020 - Springer
… are heterogeneous autoimmune conditions of skeletal muscle inflammation and weakness.
… for IIM due to the delay to IIM diagnosis, all of which may alter mRNA and miRNA expression. …

Noncoding RNAs in Duchenne and Becker muscular dystrophies: role in pathogenesis and future prognostic and therapeutic perspectives

R Brusa, F Magri, N Bresolin, GP Comi… - Cellular and Molecular Life …, 2020 - Springer
… Duchenne muscular dystrophy (DMD) is one of the most common neuromuscular disorders
in childhood… Moreover, the analysis of miRNA expression may improve our knowledge of the …

Muscle weakness in myositis: MicroRNA‐mediated dystrophin reduction in a myositis mouse model and human muscle biopsies

TB Kinder, CR Heier, CB Tully… - Arthritis & …, 2020 - Wiley Online Library
… and miRNA expression and histologic features in the muscle tissue… and other muscle disorders,
in particular, Duchenne muscular … Previously, we described 2 distinct sets of microRNAs (…

The biomarker potential of miRNAs in myotonic dystrophy type I

E Koehorst, A Ballester-Lopez… - Journal of Clinical …, 2020 - mdpi.com
… In addition, miRNA expression profiles are different in the … of the disease present a unique
challenge in terms of disease … admitted for suspected neuromuscular disorders. This can …

[PDF][PDF] MicroRNAs and HDAC4 protein expression in the skeletal muscle of ALS patients

V Pegoraro, R Marozzo, C Angelini - Clinical neuropathology, 2020 - researchgate.net
… individuals with no neuromuscular disorders were selected. … Microscopic atrophy grading
was performed by two distinct … tion, miRNA expression levels were normalized on miRNA 39-3p …

Influence of microRNAs and exosomes in muscle health and diseases

NT Lam, M Gartz, L Thomas, M Haberman… - Journal of muscle …, 2020 - Springer
… during myogenesis, they are also involved in muscle regeneration (Galimov et al. 2016;
Nie et al. 2016). Distinct patterns of miRNA expression have been observed in murine cardiac …