Allosteric Interactions between Adenosine A2A and Dopamine D2 Receptors in Heteromeric Complexes: Biochemical and Pharmacological Characteristics, and …
K Prasad, EFJ de Vries, PH Elsinga… - International Journal of …, 2021 - mdpi.com
… Adenosine appears to regulate the properties of D 2 R via its interaction with A 2A R. Direct
receptor–receptor interactions in striatal … for 3 h, the distribution of the receptors in the plasma …
receptor–receptor interactions in striatal … for 3 h, the distribution of the receptors in the plasma …
Topography and distribution of adenosine A2A and dopamine D2 receptors in the human Subthalamic Nucleus
… (B) D 2 R immunoreactivity in the striatum and (C) in the … distribution of A 2A adenosine
receptor in the basal ganglia reveals a marker expression of the receptor in the striatum (G) and …
receptor in the basal ganglia reveals a marker expression of the receptor in the striatum (G) and …
Adenosine A2A-dopamine D2 receptor-receptor interaction in neurons and astrocytes: Evidence and perspectives
… biochemical and functional evidence that structural receptor-… distribution of immunogold-labeled
A 2A and D 2 receptor … striatal astrocytes express both adenosine A 2A receptors 81 …
A 2A and D 2 receptor … striatal astrocytes express both adenosine A 2A receptors 81 …
Decreased striatal adenosine A2A-dopamine D2 receptor heteromerization in schizophrenia
M Valle-León, LF Callado, E Aso… - …, 2021 - nature.com
… of adenosine or alterations in the density of adenosine A 2A receptors (A 2A Rs) or their
degree of functional heteromerization with dopamine D 2 receptors (D 2 R). In the present study, …
degree of functional heteromerization with dopamine D 2 receptors (D 2 R). In the present study, …
Adenosine A2A receptor in schizophrenia: an in vivo brain PET imaging study
… distribution were assessed with Kolmogorov–Smirnov tests. Since PET and clinical data were
normally distributed we … We found no difference in striatal A2A binding potential between …
normally distributed we … We found no difference in striatal A2A binding potential between …
… treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor–receptor interactions in rat dorsal striatum without increasing significantly …
W Romero-Fernandez, Z Zhou, S Beggiato… - Pharmacological …, 2020 - Springer
… there exist antagonistic adenosine A2A receptor (A2AR)-dopamine (DA) D2 receptor (D2R) …
in the rat dorsal striatum, as demonstrated with biochemical binding techniques using D2R …
in the rat dorsal striatum, as demonstrated with biochemical binding techniques using D2R …
Increased ATP Release and Higher Impact of Adenosine A2A Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson's Disease
FQ Gonçalves, FC Matheus, HB Silva, JI Real… - Molecular …, 2023 - Springer
… allowed defining the pattern of ATP release from stimulated striatal nerve terminals and
the distribution of P2 receptors in striatal synapses, which were surprisingly devoid of major …
the distribution of P2 receptors in striatal synapses, which were surprisingly devoid of major …
Adenosine A2A Receptors as Biomarkers of Brain Diseases
A Moreira-de-Sá, VS Lourenço, PM Canas… - Frontiers in …, 2021 - frontiersin.org
… Adenosine receptors are most abundant in the brain, where adenosine acts through inhibitory
A 1 receptors to decrease activity/noise and through facilitatory A 2A receptors (A 2A R) to …
A 1 receptors to decrease activity/noise and through facilitatory A 2A receptors (A 2A R) to …
Adenosine A2A receptor availability in patients with early- and moderate-stage Parkinson's disease
… in A 2A receptor availability in the striatum and pallidum of … a homogenous distribution
throughout the striatum and are … Activation of A 2A receptors at the dendritic level in the striatum or …
throughout the striatum and are … Activation of A 2A receptors at the dendritic level in the striatum or …
Dopamine D2 and Adenosine A2A Receptors Interaction on Ca2+ Current Modulation in a Rodent Model of Parkinsonism
EA Rendón-Ochoa, M Padilla-Orozco… - ASN …, 2022 - journals.sagepub.com
… To do that, cumulative distribution functions were plotted … biochemical antagonistic
interactions reported between both … Blocking striatal adenosine A2A receptors: A new strategy for …
interactions reported between both … Blocking striatal adenosine A2A receptors: A new strategy for …