… pre-clinical models has not always translated into clinical trials. … macrophage heterogeneity
within the pancreatic tumor microenvironment, and examine the contribution of macrophages …

… In the past decade, substantial advances have been made in understanding the biology
of tumour-associated macrophages (TAMs), and their clinical relevance is emerging. A …

… parallelly compared the drug delivery efficiency of exosomes from pancreatic cancer cells, …
, the clinical significance of reducing the TAM population has been enlightened in clinical …

… In this study, we investigated the role of tumor-associated macrophages (TAMs) in the
progression of pancreatic ductal adenocarcinoma (PDAC). PDAC patients with higher levels of …

… types were distributed differently in ANT and PDAC, including M0, M1, and M2 macrophages
(… and fraction of macrophages in PDAC compared to the control pancreas in CRA001160, …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive
and deadliest cancer worldwide, with an overall survival (OS) rate, all stages combined, of …

… Notably, cluster 2 macrophages also served as the progenitor of tumor-infiltrating macrophages,
and cluster 3 macrophages were distributed broadly in the termini of State2. Further, …

… Objective Most patients with pancreatic ductal … and moderate CD68 + tumour-associated
macrophages counts (cyan… displayed significant heterogeneity regarding the distribution pattern …

… and specific variability in distribution within the pancreatic parenchyma, plays a key role in
… on the spatial distribution, type of subpopulation involved, and accompanying macrophage …

… of pancreatic ductal adenocarcinoma (PDA) and control adjacent normal pancreatic tissue.
… first 24 hours, the CFSE dyes became diffusely distributed throughout the cell in 24–48 hours …