Change in Expression of 5-HT 6 Receptor at Different Stages of Alzheimer's Disease: A Postmortem Study with the PET Radiopharmaceutical [18F] 2FNQ1P
P Courault, S Emery, S Bouvard, F Liger… - Journal of …, 2020 - content.iospress.com
… is one of the most recently identified serotonin receptors in … identified, first in rat [3,4] and
then in the human brain [5]. The … the pharmacological hypothesis that 5-HT 6 receptor blockade …
then in the human brain [5]. The … the pharmacological hypothesis that 5-HT 6 receptor blockade …
Preclinical validation of [18F] 2FNQ1P as a specific PET radiotracer of 5-HT6 receptors in rat, pig, non-human primate and human brain tissue
S Emery, S Fieux, B Vidal, P Courault… - Nuclear Medicine and …, 2020 - Elsevier
… Serotonin receptor subtype-6 of (5-HT 6 ) is one of the more … a pharmacological profile suitable
for in-vivo study in humans. … for studying 5-HT 6 receptor density and distribution in animal …
for in-vivo study in humans. … for studying 5-HT 6 receptor density and distribution in animal …
Ligand bias and inverse agonism on 5‐HT2A receptor‐mediated modulation of G protein activity in post‐mortem human brain
I Muneta‐Arrate, P Miranda‐Azpiazu… - … of Pharmacology, 2024 - Wiley Online Library
… Even so, if that possibility was true and 5-HT was present, drugs … relative efficacy at serotonin
type 2A and 2C receptors: Evidence for … The pharmacology and distribution of human 5-…
type 2A and 2C receptors: Evidence for … The pharmacology and distribution of human 5-…
Serotonin type 6 and 7 receptors as a novel therapeutic target for the treatment of schizophrenia
EW Tsegay, DG Demise, NA Hailu… - … Disease and Treatment, 2020 - Taylor & Francis
… and pharmacological differences serotonin receptors (5-… brain areas with higher distribution
of 5-HT 6 and 7 receptors … HT7Rs at prefrontal cortex in post mortem studies of schizophrenic …
of 5-HT 6 and 7 receptors … HT7Rs at prefrontal cortex in post mortem studies of schizophrenic …
Opposite alterations of 5HT2A receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile
R Diez-Alarcia, C Muguruza, G Rivero… - Translational …, 2021 - nature.com
… The status of serotonin 5HT 2A receptors (5HT 2A Rs) in … This study investigates 5HT 2A R
density in the post-mortem … agonist properties on 5HT 2A Rs in post-mortem human brain 13,…
density in the post-mortem … agonist properties on 5HT 2A Rs in post-mortem human brain 13,…
[HTML][HTML] 5-HT7 receptors in Alzheimer's disease
… Post-mortem studies have reported decreased 5-HT levels in … of serotonergic 5-HT 7 receptors
in postmortem brain samples … of pharmacologic blockade and genetic ablation of 5-HT 7 …
in postmortem brain samples … of pharmacologic blockade and genetic ablation of 5-HT 7 …
The implication of 5-HT receptor family members in aggression, depression and suicide: similarity and difference
NK Popova, AS Tsybko, VS Naumenko - International journal of molecular …, 2022 - mdpi.com
… pharmacological evidence on the role of 5-HT 1A receptors … However, the fact that the
post-mortem samples are largely … Serotonin 2A (5-HT 2A ), 5-HT 2B and 5-HT 2C receptors are …
post-mortem samples are largely … Serotonin 2A (5-HT 2A ), 5-HT 2B and 5-HT 2C receptors are …
5-HT2A receptor-mediated Gαq/11 activation in psychiatric disorders: A postmortem study
Y Odagaki, M Kinoshita, JJ Meana… - The World Journal of …, 2021 - Taylor & Francis
… 5-HT 2A receptor-mediated signalling pathway through Gα q/11 activation in psychiatric
patients by using post-mortem brain … In the present study, the pharmacological parameters of …
patients by using post-mortem brain … In the present study, the pharmacological parameters of …
Serotonin modulation of hippocampal functions: From anatomy to neurotherapeutics
… and the link between 5-HT and the hippocampus … the distribution and the functional roles
of the 5-HT receptors in the hippocampal region in health and disease. The impact of the 5-HT …
of the 5-HT receptors in the hippocampal region in health and disease. The impact of the 5-HT …
Post-mortem toxicology: a systematic review of death cases involving synthetic cannabinoid receptor agonists
… , due to similarities of their pharmacological profile to Δ9-THC … can also bind to glutamatergic,
serotonin (5-HT), opioid, and … in tissues, and the post-mortem distribution of the drugs can …
serotonin (5-HT), opioid, and … in tissues, and the post-mortem distribution of the drugs can …