Inflammation and atherosclerosis: what is on the horizon?
N Ruparelia, R Choudhury - Heart, 2020 - heart.bmj.com
… Each of these represent very different biology and there is therefore … macrophages.
Experimental studies have confirmed improved macrophage specificity in atherosclerotic …
Experimental studies have confirmed improved macrophage specificity in atherosclerotic …
[HTML][HTML] Novel biomarkers of atherosclerotic vascular disease—Latest insights in the research field
… various signaling pathways involved in atherosclerosis have led to the development of potential
new biomarkers, with key role … accumulation of macrophages in atherosclerotic lesions […
new biomarkers, with key role … accumulation of macrophages in atherosclerotic lesions […
[HTML][HTML] Immune cell profiling in atherosclerosis: role in research and precision medicine
DM Fernandez, C Giannarelli - Nature Reviews Cardiology, 2022 - nature.com
… role of macrophages in atherosclerosis and provide the important concept that manipulating
macrophage polarization to restore their reparative functions is … the diversity of macrophage …
macrophage polarization to restore their reparative functions is … the diversity of macrophage …
Inflammation in atherosclerosis—no longer a theory
P Libby - Clinical chemistry, 2021 - academic.oup.com
… with different functions. Among them, Th1 cells produce interferon (IFN)-γ and TNF, are highly
proinflammatory, and strongly stimulate macrophage activation and vascular inflammation. …
proinflammatory, and strongly stimulate macrophage activation and vascular inflammation. …
Inflammatory markers related to innate and adaptive immunity in atherosclerosis: implications for disease prediction and prospective therapeutics
LZ Hong, Q Xue, H Shao - Journal of inflammation research, 2021 - Taylor & Francis
… Monocytes infiltrate the inflammation site and differentiate into macrophages, which engulf
… evidence suggests that various inflammatory factors may be increased in different phases of …
… evidence suggests that various inflammatory factors may be increased in different phases of …
[HTML][HTML] Macrophage plasticity and atherosclerosis therapy
P Lin, HH Ji, YJ Li, SD Guo - Frontiers in molecular biosciences, 2021 - frontiersin.org
… of atherosclerosis, macrophages with high heterogeneity and plasticity raise the hope …
atherosclerosis regression. This review will focus on the macrophage phenotypic diversity, its role …
atherosclerosis regression. This review will focus on the macrophage phenotypic diversity, its role …
[HTML][HTML] Macrophages and foam cells: Brief overview of their role, linkage, and targeting potential in atherosclerosis
AV Poznyak, NG Nikiforov, AV Starodubova… - Biomedicines, 2021 - mdpi.com
… exist in the activation continuum, and that the M1/M2 classification system is a very strong
simplification of the heterogeneity of macrophages and their various functions [49]. …
simplification of the heterogeneity of macrophages and their various functions [49]. …
Macrophages in atherosclerosis regression
TJ Barrett - Arteriosclerosis, thrombosis, and vascular biology, 2020 - Am Heart Assoc
… suggests that macrophages exist on an activation continuum and that the M1/M2 classification
system is an oversimplification of macrophage heterogeneity and their diverse functions. …
system is an oversimplification of macrophage heterogeneity and their diverse functions. …
[HTML][HTML] Inflammatory chemokines in atherosclerosis
… on the diverse roles of chemokines in atherosclerosis, a chronic inflammatory disease of the
… overexpressed in CD68+ macrophage rich areas of human atherosclerotic lesions, however …
… overexpressed in CD68+ macrophage rich areas of human atherosclerotic lesions, however …
[HTML][HTML] Roles of macrophages in atherogenesis
… This article reviews recent advances regarding the roles of macrophages in different stages
… to advanced atherosclerosis. Macrophage-based therapies for atherosclerosis management …
… to advanced atherosclerosis. Macrophage-based therapies for atherosclerosis management …