An integrative gene network-based approach to uncover the cellular and molecular infrastructures of schizophrenia
A Bozorgmehr, B Sadeghi, EST Zavari, E Bahrami… - Life Sciences, 2020 - Elsevier
… terms of structure and function during schizophrenia pathogenesis [6]. … of the
schizophrenia-related gene set in different regions of … that genetic variation in the serotonin …
schizophrenia-related gene set in different regions of … that genetic variation in the serotonin …
[HTML][HTML] Patterns of convergence and divergence between bipolar disorder type I and type II: evidence from integrative genomic analyses
Y Huang, Y Liu, Y Wu, Y Tang, M Zhang… - Frontiers in Cell and …, 2022 - frontiersin.org
… TWAS data implicated different genes affecting BD I and II … II share continuous genetic
structures with schizophrenia and … whether omitting each genetic variant from analysis differs from …
structures with schizophrenia and … whether omitting each genetic variant from analysis differs from …
[HTML][HTML] Progressive trajectories of schizophrenia across symptoms, genes, and the brain
… Our convergent results indicate that progressive symptoms and functional neuroimaging …
Heterogeneous symptoms exist in different stages of schizophrenia, and the disease …
Heterogeneous symptoms exist in different stages of schizophrenia, and the disease …
Systems-level analysis of genetic variants reveals functional and spatiotemporal context in treatment-resistant schizophrenia
… functional and spatiotemporal context for TRS, suggesting that genotypic variation may
converge to … SCZ individuals, which could be different from those occurring in adolescence and …
converge to … SCZ individuals, which could be different from those occurring in adolescence and …
Exploring the genetic overlap between twelve psychiatric disorders
… The meta-analytic signal was driven by schizophrenia, … regions that harbor genetic variants
associated to multiple … for gene sets, tissues or cell types, we observed convergence among …
associated to multiple … for gene sets, tissues or cell types, we observed convergence among …
Convergent brain microstructure across multiple genetic models of schizophrenia and autism spectrum disorder: a feasibility study
BR Barnett, CP Casey, M Torres-Velázquez… - Magnetic resonance …, 2020 - Elsevier
… used to explore differences in the structural and functional … neurite density across different
genetic variants in psychiatric … between genetic variants of ASD and schizophrenia, reinforcing …
genetic variants in psychiatric … between genetic variants of ASD and schizophrenia, reinforcing …
Converging pathways found in copy number variation syndromes with high schizophrenia risk
… contribution of these genetic variants to mental illness, we need … presentation of schizophrenia
risk genes from different sources in … search function to extract genes and genetic variants …
risk genes from different sources in … search function to extract genes and genetic variants …
Brain transcriptional regulatory architecture and schizophrenia etiology converge between East Asian and European ancestral populations
… and how such genetic differences contribute to health and … of risk variants for psychiatric
disorders across diverse populations 2,3 . … the biological function of these candidate genes, we …
disorders across diverse populations 2,3 . … the biological function of these candidate genes, we …
Cortical cellular diversity and development in schizophrenia
… to conducting cell type-specific functional genomic studies in … risk attributed to common
genetic variation. For instance, an … of schizophrenia to improve and converge at the cellular level. …
genetic variation. For instance, an … of schizophrenia to improve and converge at the cellular level. …
Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in …
… share substantial genetic variants (74–96%) with schizophrenia, and … and for brain volumetric
phenotypes were based on different … Combining the above functional enrichment and gene …
phenotypes were based on different … Combining the above functional enrichment and gene …