Ca2+ Signaling and Src Functions in Tumor Cells

A Villalobo - Biomolecules, 2023 - mdpi.com
… by a unique domain specific to each Src-family kinase (SFK) … the myristoylated peptide by
protein kinase C (PKC) at both … , we prepared phosphomimetic CaM mutants by substituting …

Defining the Molecular Mechanisms that Govern Par-3 Mediated Polarization of the Par-Complex

R Holly - 2020 - scholarsbank.uoregon.edu
… polarity is the protein kinase, atypical Protein Kinase C (aPKC)… The Protein Kinase C (PKC)
family of kinases includes 12 … later), larvae were dissected within 20 minutes into Schneider’s …

Regulation of the SIRT1 signaling pathway in NMDA-induced Excitotoxicity

…, J Wu, J Ma, P Si, L Yin, Y Zhang, LJ Yan, C Zhang - Toxicology Letters, 2020 - Elsevier
… Ca 2+ -dependent PKC makes a major contribution to PKC activation during NMDA
insults. … is PKC-dependent. It is well known that HuR is a substrate for protein kinase C. …

Dissecting Transient Protein Interactions Implicated in Cardiovascular Disease: G Protein-Coupled Receptors and Cardiac Myosin-Binding Protein C

AM Touma - 2021 - search.proquest.com
… This study provides an initial model for the impact of G-peptide interactions in … by
cMyBP-C remains unclear due to experimental challenges in dissecting these weak, …

Regulation of TORC2 Function and Localization in Yeast

A Emmerstorfer-Augustin… - Annual Review of Cell and …, 2023 - annualreviews.org
… Like other large protein kinases, folding of a TOR … Furthermore, we found that both a
phosphomimetic Avo2(9E) allele … cerevisiae as a model eukaryotic organism in which to dissect

O-GlcNAc modification of casein kinase 2 alpha alters the phosphoproteome

PA Schwein - 2022 - search.proquest.com
… , or with an alanine mutation at S497. Cell lysates were alkylated, then reacted with
DBCO-PEG5kDa, which bound to OGlcNAz-modified proteins and allowed visualization of O-GlcNAc …

… dephosphorylation of cyclase-associated protein 1 by antagonistic signaling through cyclin-dependent kinase 5 and cAMP are critical for the protein functions in actin …

H Zhang, A Ramsey, Y Xiao, U Karki… - … and cellular biology, 2020 - Taylor & Francis
… In dissecting further phosphoregulatory cell signals for CAP1… the phosphomimetic and the
nonphosphorylatable mutant of … ), an activator of protein kinase C that we previously found to …

Regulation of DNA damage response and homologous recombination repair by microRNA in human cells exposed to ionizing radiation

M Szatkowska, R Krupa - Cancers, 2020 - mdpi.com
mutations of 3′UTR microRNA binding sites were more often present in the mitogen-activated
protein kinase … chromatin modification, which allows other DDR protein components to be …

TOR complex 2 is a master regulator of plasma membrane homeostasis

J Thorner - Biochemical Journal, 2022 - portlandpress.com
… (iv) a C-terminal pleckstrin homology (PH) domain specific for … Correspondingly, a
phosphomimetic Avo2 9E allele and an … affects Fpk1 control of yet another protein kinase, Akl1 …

The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1

…, S Bozkurt, P Wurzel, S Gauer, G Imre, C Münch… - Cells, 2023 - mdpi.com
… To test whether in colon carcinoma cells TRIM25 is also a target of constitutive ubiquitination,
we used ubiquitination affinity beads, which allow the capturing of ubiquitinated proteins