… Here, we provide an overview of the many different … , more specific, and less toxic molecules
can be identified for the … least) two pathways for receptor-mediated endocytosis of suramin in …

… In the last two decades, appreciable progress has been … , chemotherapeutic agents have
significant toxicity and badly … In a cohort study with 15,052 colorectal cancer patients, that …

… are needed to explore its potential as a therapeutic agent. … In colorectal cancer, theobromine
was able to induce … , and its potential toxicity, ADMET prediction offers valuable insights into …

… truncated suramin derivatives were ineffective against the tumor cell … )thiazol-2-yl urea
derivatives as therapeutic agents) this year, … activity against human colon cancer cells, underwent …

… to provide a viable solution. Here, we demonstrate that the reduction of LL-37 toxicity might
be … Moreover, a comparison with other therapeutic agents having common features unveiled …

… show potential as novel therapeutic agents for their anti-… of suramin was understood, less
toxic and more specific new … , suramin has been tested for NSCLC’s, prostate cancer, and …

… that there are two types of lesions in the brain of AD patients, … Colorectal cancer is the second
leading cause of cancer … time and cost but also has very high safety and toxicity risk [135]…

… resistance in MM patients, neuro-toxicities, and little efficacy in … therapeutic agent for multiple
myeloma (MM) and mantle cell … , BTZ has shown significant anticancer activity in plasma cell …

… to unmodified suramin and these are also less toxic [110]. … in vitro, and it has been proposed
as a novel therapeutic agent to … PPS or isotonic saline was injected twice weekly for 6 weeks …

… , which leads to colorectal cancer cell development. (E) In AD … Recently, new applications
of suramin were gradually being … to PPP5C while reducing toxicity remains a challenge. …